Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells

E. Böhmová, D. Machová, M. Pechar, R. Pola, K. Venclíková, O. Janoušková, T. Etrych

. 2018 ; 67 (Suppl. 2) : S267-S279.
. 2018 ; () : S267-S279.

Jazyk angličtina Země Česko

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc19005349

Cell-penetrating compounds are substances that enhance the cellular uptake of various molecular cargoes that do not easily cross the cellular membrane. The majority of cell-penetrating compounds described in the literature are cell-penetrating peptides (CPPs). This review summarizes the various structural types of cell-penetrating compounds, with the main focus on CPPs. The authors present a brief overview of the history of CPPs, discuss the various types of conjugation of CPPs to biologically active cargoes intended for cell internalization, examine the cell-entry mechanisms of CPPs, and report on the applications of CPPs in research and in preclinical and clinical studies.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19005349
003      
CZ-PrNML
005      
20210519153110.0
007      
ta
008      
190204s2018 xr a f 000 0|eng||
009      
AR
024    7_
$a 10.33549/physiolres.933975 $2 doi
035    __
$a (PubMed)30379549
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Böhmová, Eliška $7 xx0232781 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
245    10
$a Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells / $c E. Böhmová, D. Machová, M. Pechar, R. Pola, K. Venclíková, O. Janoušková, T. Etrych
520    9_
$a Cell-penetrating compounds are substances that enhance the cellular uptake of various molecular cargoes that do not easily cross the cellular membrane. The majority of cell-penetrating compounds described in the literature are cell-penetrating peptides (CPPs). This review summarizes the various structural types of cell-penetrating compounds, with the main focus on CPPs. The authors present a brief overview of the history of CPPs, discuss the various types of conjugation of CPPs to biologically active cargoes intended for cell internalization, examine the cell-entry mechanisms of CPPs, and report on the applications of CPPs in research and in preclinical and clinical studies.
650    _2
$a sekvence aminokyselin $7 D000595
650    _2
$a zvířata $7 D000818
650    _2
$a buněčná membrána $x účinky léků $x metabolismus $7 D002462
650    _2
$a penetrační peptidy $x aplikace a dávkování $x genetika $x metabolismus $7 D057846
650    _2
$a lékové transportní systémy $x metody $7 D016503
650    _2
$a endocytóza $x účinky léků $x fyziologie $7 D004705
650    _2
$a lidé $7 D006801
655    _2
$a časopisecké články $7 D016428
655    _2
$a přehledy $7 D016454
700    1_
$a Machová, Daniela $7 xx0232787 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
700    1_
$a Pechar, Michal, $d 1967- $7 xx0141621 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
700    1_
$a Pola, Robert $7 xx0232782 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
700    1_
$a Venclíková, Kristýna $7 xx0232789 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
700    1_
$a Janoušková, Olga $7 xx0100922 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
700    1_
$a Etrych, Tomáš $7 xx0068504 $u Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Prague, Czech Republic
773    0_
$w MED00003824 $t Physiological research $x 1802-9973 $g Roč. 67, Suppl. 2 (2018), s. S267-S279
773    0_
$t Recent achievements from Otto Wichterle Innovation Centers of Polymeric Materials and Biocev research project - part II $g (2018), s. S267-S279 $w MED00206980
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30379549 $y Pubmed
910    __
$a ABA008 $b A 4120 $c 266 $y 4 $z 0
990    __
$a 20190204 $b ABA008
991    __
$a 20210519153108 $b ABA008
999    __
$a ok $b bmc $g 1376659 $s 1043554
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 67 $c Suppl. 2 $d S267-S279 $i 1802-9973 $m Physiological research $n Physiol. Res. (Print) $x MED00003824
BMC    __
$a 2018 $d S267-S279 $m Recent achievements from Otto Wichterle Innovation Centers of Polymeric Materials and Biocev research project - part II $x MED00206980
LZP    __
$b NLK118 $a Pubmed-20190204
Zpět

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace