-
Je něco špatně v tomto záznamu ?
Mutants of dermatophytes resistant to ketoconazole
K. Lenhart, A. Merkunová,
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články
PubMed
7778498
Knihovny.cz E-zdroje
- MeSH
- antibiotická rezistence MeSH
- ketokonazol farmakologie MeSH
- Microsporum účinky léků genetika MeSH
- mutace MeSH
- Trichophyton účinky léků genetika MeSH
- Publikační typ
- časopisecké články MeSH
Authors describe the frequency and properties of mutants resistant to ketoconazole, obtained from the dermatophytes Microsporum gypseum and Trichophyton mentagrophytes. Spontaneous mutants occurred with the frequency of 10(-9) to spore and nucleus. Ultraviolet radiation increased the frequency of mutants by two numeric orders. The resistance level was relatively small in both types of mutants (RL within the range of 2-5).
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19008701
- 003
- CZ-PrNML
- 005
- 20190307110657.0
- 007
- ta
- 008
- 190307s1994 xr f 000 0|eng||
- 009
- AR
- 035 __
- $a (PubMed)7778498
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Lenhart, Karel, $u Institute of Biology, Medical faculty Olomouc, Czech Republic. $d 1937- $7 jn20000401624
- 245 10
- $a Mutants of dermatophytes resistant to ketoconazole / $c K. Lenhart, A. Merkunová,
- 520 9_
- $a Authors describe the frequency and properties of mutants resistant to ketoconazole, obtained from the dermatophytes Microsporum gypseum and Trichophyton mentagrophytes. Spontaneous mutants occurred with the frequency of 10(-9) to spore and nucleus. Ultraviolet radiation increased the frequency of mutants by two numeric orders. The resistance level was relatively small in both types of mutants (RL within the range of 2-5).
- 650 _2
- $a antibiotická rezistence $7 D004352
- 650 _2
- $a ketokonazol $x farmakologie $7 D007654
- 650 _2
- $a Microsporum $x účinky léků $x genetika $7 D008864
- 650 _2
- $a mutace $7 D009154
- 650 _2
- $a Trichophyton $x účinky léků $x genetika $7 D014249
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Merkunová, Alena, $d 1942- $7 kup19940000064371
- 773 0_
- $w MED00011326 $t Acta Universitatis Palackianae Olomucensis Facultatis Medicae $x 0301-2514 $g Roč. 137, č. - (1994), s. 15-17
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/7778498 $y Pubmed
- 910 __
- $a ABA008 $b A 1502 $c sign $y a $z 0
- 990 __
- $a 20190307 $b ABA008
- 991 __
- $a 20190307111012 $b ABA008
- 999 __
- $a ok $b bmc $g 1382624 $s 1046959
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 1994 $b 137 $c $d 15-17 $i 0301-2514 $m Acta Universitatis Palackianae Olomucensis Facultatis medicae. Biomedical papers $n Acta Univ. Palacki. Olomuc. Fac. med., Biomed. Pap. $x MED00011326
- LZP __
- $a Pubmed-20190307