Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

Electrical Stimulation Modulates High γ Activity and Human Memory Performance

MT. Kucewicz, BM. Berry, V. Kremen, LR. Miller, F. Khadjevand, Y. Ezzyat, JM. Stein, P. Wanda, MR. Sperling, R. Gorniak, KA. Davis, BC. Jobst, RE. Gross, B. Lega, SM. Stead, DS. Rizzuto, MJ. Kahana, GA. Worrell,

. 2018 ; 5 (1) : . [pub] 20180202

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články, multicentrická studie, práce podpořená grantem, Research Support, U.S. Gov't, Non-P.H.S.

Perzistentní odkaz   https://www.medvik.cz/link/bmc19012868

Direct electrical stimulation of the brain has emerged as a powerful treatment for multiple neurological diseases, and as a potential technique to enhance human cognition. Despite its application in a range of brain disorders, it remains unclear how stimulation of discrete brain areas affects memory performance and the underlying electrophysiological activities. Here, we investigated the effect of direct electrical stimulation in four brain regions known to support declarative memory: hippocampus (HP), parahippocampal region (PH) neocortex, prefrontal cortex (PF), and lateral temporal cortex (TC). Intracranial EEG recordings with stimulation were collected from 22 patients during performance of verbal memory tasks. We found that high γ (62-118 Hz) activity induced by word presentation was modulated by electrical stimulation. This modulatory effect was greatest for trials with "poor" memory encoding. The high γ modulation correlated with the behavioral effect of stimulation in a given brain region: it was negative, i.e., the induced high γ activity was decreased, in the regions where stimulation decreased memory performance, and positive in the lateral TC where memory enhancement was observed. Our results suggest that the effect of electrical stimulation on high γ activity induced by word presentation may be a useful biomarker for mapping memory networks and guiding therapeutic brain stimulation.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc19012868
003      
CZ-PrNML
005      
20190425150325.0
007      
ta
008      
190405s2018 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1523/ENEURO.0369-17.2018 $2 doi
035    __
$a (PubMed)29404403
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Kucewicz, Michal T $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
245    10
$a Electrical Stimulation Modulates High γ Activity and Human Memory Performance / $c MT. Kucewicz, BM. Berry, V. Kremen, LR. Miller, F. Khadjevand, Y. Ezzyat, JM. Stein, P. Wanda, MR. Sperling, R. Gorniak, KA. Davis, BC. Jobst, RE. Gross, B. Lega, SM. Stead, DS. Rizzuto, MJ. Kahana, GA. Worrell,
520    9_
$a Direct electrical stimulation of the brain has emerged as a powerful treatment for multiple neurological diseases, and as a potential technique to enhance human cognition. Despite its application in a range of brain disorders, it remains unclear how stimulation of discrete brain areas affects memory performance and the underlying electrophysiological activities. Here, we investigated the effect of direct electrical stimulation in four brain regions known to support declarative memory: hippocampus (HP), parahippocampal region (PH) neocortex, prefrontal cortex (PF), and lateral temporal cortex (TC). Intracranial EEG recordings with stimulation were collected from 22 patients during performance of verbal memory tasks. We found that high γ (62-118 Hz) activity induced by word presentation was modulated by electrical stimulation. This modulatory effect was greatest for trials with "poor" memory encoding. The high γ modulation correlated with the behavioral effect of stimulation in a given brain region: it was negative, i.e., the induced high γ activity was decreased, in the regions where stimulation decreased memory performance, and positive in the lateral TC where memory enhancement was observed. Our results suggest that the effect of electrical stimulation on high γ activity induced by word presentation may be a useful biomarker for mapping memory networks and guiding therapeutic brain stimulation.
650    _2
$a dospělí $7 D000328
650    _2
$a mozková kůra $x fyziologie $7 D002540
650    _2
$a refrakterní epilepsie $x patofyziologie $7 D000069279
650    12
$a elektrická stimulace $7 D004558
650    12
$a elektrokortikografie $7 D000069280
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a gama rytmus EEG $x fyziologie $7 D065818
650    _2
$a lidé $7 D006801
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a paměť $x fyziologie $7 D008568
650    _2
$a lidé středního věku $7 D008875
650    _2
$a mladý dospělý $7 D055815
655    _2
$a časopisecké články $7 D016428
655    _2
$a multicentrická studie $7 D016448
655    _2
$a práce podpořená grantem $7 D013485
655    _2
$a Research Support, U.S. Gov't, Non-P.H.S. $7 D013486
700    1_
$a Berry, Brent M $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
700    1_
$a Kremen, Vaclav $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905. Czech Institute of Informatics, Robotics and Cybernetics, Czech Technical University, Prague, 166 36 Czech Republic.
700    1_
$a Miller, Laura R $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
700    1_
$a Khadjevand, Fatemeh $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
700    1_
$a Ezzyat, Youssef $u Department of Psychology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Stein, Joel M $u Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Wanda, Paul $u Department of Psychology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Sperling, Michael R $u Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107.
700    1_
$a Gorniak, Richard $u Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107.
700    1_
$a Davis, Kathryn A $u Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Jobst, Barbara C $u Department of Neurology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
700    1_
$a Gross, Robert E $u Department of Neurosurgery, Emory University, Atlanta, GA 30307.
700    1_
$a Lega, Bradley $u Department of Neurosurgery, UT Southwestern Medical Center, Dallas, TX 75390.
700    1_
$a Stead, S Matt $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
700    1_
$a Rizzuto, Daniel S $u Department of Psychology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Kahana, Michael J $u Department of Psychology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
700    1_
$a Worrell, Gregory A $u Department of Neurology, Mayo Clinic, Rochester, MN 55905. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905.
773    0_
$w MED00198701 $t eNeuro $x 2373-2822 $g Roč. 5, č. 1 (2018)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29404403 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20190405 $b ABA008
991    __
$a 20190425150400 $b ABA008
999    __
$a ok $b bmc $g 1392178 $s 1051173
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 5 $c 1 $e 20180202 $i 2373-2822 $m eNeuro $n eNeuro $x MED00198701
LZP    __
$a Pubmed-20190405
Zpět

Najít záznam

Citační ukazatele

Možnosti archivace