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Resistive pulse sensing as particle counting and sizing method in microfluidic systems: Designs and applications review

T. Vaclavek, J. Prikryl, F. Foret,

. 2019 ; 42 (1) : 445-457. [pub] 20181203

Jazyk angličtina Země Německo

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/bmc19028076

Grantová podpora
16-09283Y Czech Science Foundation
18-03367Y Czech Science Foundation
P206/12/G014 Czech Science Foundation
RVO: 68081715 Czech Academy of Sciences

Resistive pulse sensing is a well-known and established method for counting and sizing particles in ionic solutions. Throughout its development the technique has been expanded from detection of biological cells to counting nanoparticles and viruses, and even registering individual molecules, e.g., nucleotides in nucleic acids. This technique combined with microfluidic or nanofluidic systems shows great potential for various bioanalytical applications, which were hardly possible before microfabrication gained the present broad adoption. In this review, we provide a comprehensive overview of microfluidic designs along with electrode arrangements with emphasis on applications focusing on bioanalysis and analysis of single cells that were reported within the past five years.

Citace poskytuje Crossref.org

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