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The Role of Nutraceuticals in Statin Intolerant Patients
M. Banach, AM. Patti, RV. Giglio, AFG. Cicero, AG. Atanasov, G. Bajraktari, E. Bruckert, O. Descamps, DM. Djuric, M. Ezhov, Z. Fras, S. von Haehling, N. Katsiki, M. Langlois, G. Latkovskis, GBJ. Mancini, DP. Mikhailidis, O. Mitchenko, PM....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
NLK
Free Medical Journals
od 1983 do Před 1 rokem
Open Access Digital Library
od 1998-01-01
- MeSH
- dyslipidemie dietoterapie farmakoterapie MeSH
- klinická studie jako téma MeSH
- lidé MeSH
- potravní doplňky * MeSH
- statiny škodlivé účinky MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Statins are the most common drugs administered for patients with cardiovascular disease. However, due to statin-associated muscle symptoms, adherence to statin therapy is challenging in clinical practice. Certain nutraceuticals, such as red yeast rice, bergamot, berberine, artichoke, soluble fiber, and plant sterols and stanols alone or in combination with each other, as well as with ezetimibe, might be considered as an alternative or add-on therapy to statins, although there is still insufficient evidence available with respect to long-term safety and effectiveness on cardiovascular disease prevention and treatment. These nutraceuticals could exert significant lipid-lowering activity and might present multiple non-lipid-lowering actions, including improvement of endothelial dysfunction and arterial stiffness, as well as anti-inflammatory and antioxidative properties. The aim of this expert opinion paper is to provide the first attempt at recommendation on the management of statin intolerance through the use of nutraceuticals with particular attention on those with effective low-density lipoprotein cholesterol reduction.
1st Department of Internal Medicine Paracelsus Private Medical University Salzburg Austria
3rd Department of Internal Medicine 1st Medical Faculty Charles University Prague Czech Republic
Cardiology Clinic School of Medicine University of Athens Athens Greece
Cardiovascular Research Centre University of Zielona Gora Zielona Gora Poland
Department of Cardiology and Pneumology University of Göttingen Medical Center Göttingen Germany
Department of Cardiology Cliniques Universitaires Saint Luc Bruxells Belgium
Department of Epidemiology University of Alabama Birmingham Birmingham Alabama
Department of Internal Medicine Centres Hospitaliers Jolimont Haine Saint Paul Belgium
Department of Internal Medicine Faculty of Medicine University of Debrecen Debrecen Hungary
Department of Laboratory Medicine AZ Sint Jan Hospital Bruges Belgium
Department of Medicine and Surgery Sciences University of Bologna Bologna Italy
Department of Pharmacognosy University of Vienna Vienna Austria
Dyslipidaemia Department Institute of Cardiology AMS of Ukraine Kiev Ukraine
Heart Disease Prevention Program Division of Cardiology University of California Irvine California
Institute of Genetics and Animal Breeding of the Polish Academy of Sciences Jastrzebiec Poland
IRCCS San Raffaele Roma Rome Italy
Mount Sinai Heart Icahn School of Medicine at Mount Sinai New York New York
Citace poskytuje Crossref.org
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- $a Banach, Maciej $u Department of Hypertension, Medical University of Lodz, and the Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Zielona Gora, Poland. Electronic address: maciejbanach77@gmail.com.
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- $a The Role of Nutraceuticals in Statin Intolerant Patients / $c M. Banach, AM. Patti, RV. Giglio, AFG. Cicero, AG. Atanasov, G. Bajraktari, E. Bruckert, O. Descamps, DM. Djuric, M. Ezhov, Z. Fras, S. von Haehling, N. Katsiki, M. Langlois, G. Latkovskis, GBJ. Mancini, DP. Mikhailidis, O. Mitchenko, PM. Moriarty, P. Muntner, D. Nikolic, DB. Panagiotakos, G. Paragh, B. Paulweber, D. Pella, C. Pitsavos, Ž. Reiner, GMC. Rosano, RS. Rosenson, J. Rysz, A. Sahebkar, MC. Serban, D. Vinereanu, M. Vrablík, GF. Watts, ND. Wong, M. Rizzo, International Lipid Expert Panel (ILEP),
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- $a Statins are the most common drugs administered for patients with cardiovascular disease. However, due to statin-associated muscle symptoms, adherence to statin therapy is challenging in clinical practice. Certain nutraceuticals, such as red yeast rice, bergamot, berberine, artichoke, soluble fiber, and plant sterols and stanols alone or in combination with each other, as well as with ezetimibe, might be considered as an alternative or add-on therapy to statins, although there is still insufficient evidence available with respect to long-term safety and effectiveness on cardiovascular disease prevention and treatment. These nutraceuticals could exert significant lipid-lowering activity and might present multiple non-lipid-lowering actions, including improvement of endothelial dysfunction and arterial stiffness, as well as anti-inflammatory and antioxidative properties. The aim of this expert opinion paper is to provide the first attempt at recommendation on the management of statin intolerance through the use of nutraceuticals with particular attention on those with effective low-density lipoprotein cholesterol reduction.
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