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Surface plasmon resonance biosensor for the ultrasensitive detection of bisphenol A
CS. Xue, G. Erika, H. Jiří,
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články
Grantová podpora
16-27611A
Ministry of Health of the Czech Republic
NLK
ProQuest Central
od 2011-01-01 do Před 1 rokem
Medline Complete (EBSCOhost)
od 2003-01-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 2011-01-01 do Před 1 rokem
- MeSH
- benzhydrylové sloučeniny analýza MeSH
- biosenzitivní techniky * MeSH
- fenoly analýza MeSH
- kovové nanočástice chemie MeSH
- limita detekce MeSH
- povrchová plasmonová rezonance přístrojové vybavení MeSH
- reprodukovatelnost výsledků MeSH
- zlato chemie MeSH
- Publikační typ
- časopisecké články MeSH
Bisphenol A (BpA) is a chemical that is extensively used in common plastic products, such as food and drink containers. It can leach from the plastics and penetrate into the human body, where it acts as an endocrine disruptor with significant risks to human health. In order to minimize the exposure of human populations to BpA, methods for the detection of BpA are needed. In this work, we present a novel surface plasmon resonance (SPR) biosensor for ultrasensitive detection of BpA. Our approach combines a binding inhibition assay with functionalized gold nanoparticles for the enhancement of sensor response. We demonstrate that the developed biosensor enables the detection of BpA in a wide range of concentrations (0.01 to 100,000 ng/mL) with an extremely low limit of detection-5.2 pg/mL.
Citace poskytuje Crossref.org
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- $a Bisphenol A (BpA) is a chemical that is extensively used in common plastic products, such as food and drink containers. It can leach from the plastics and penetrate into the human body, where it acts as an endocrine disruptor with significant risks to human health. In order to minimize the exposure of human populations to BpA, methods for the detection of BpA are needed. In this work, we present a novel surface plasmon resonance (SPR) biosensor for ultrasensitive detection of BpA. Our approach combines a binding inhibition assay with functionalized gold nanoparticles for the enhancement of sensor response. We demonstrate that the developed biosensor enables the detection of BpA in a wide range of concentrations (0.01 to 100,000 ng/mL) with an extremely low limit of detection-5.2 pg/mL.
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