• Something wrong with this record ?

Toxicity of wastewater from health care facilities assessed by different bioassays

G. Jírova, A. Vlkova, M. Wittlerova, M. Dvorakova, L. Kasparova, J. Chrz, K. Kejlová, Z. Wittlingerova, M. Zimova, B. Hosíkova, J. Jiravova, H. Kolarova,

. 2019 ; 39 (6) : 441-453. [pub] -

Language English Country Sweden

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc19044975

OBJECTIVES: The purpose of this study was to determine toxicity of wastewater from hospitals in the Czech Republic using traditional and alternative toxicological methods. The pilot study comprised weekly dynamics of sewage ecotoxicity of treated wastewater from one hospital in two different seasons. A detailed investigation of wastewater ecotoxicity, genotoxicity and reprotoxicity followed in five different hospitals. METHODS: The seven following bioassays were used in this study: algal growth inhibition test (ISO 8692), Vibrio fischeri test (ISO 11348-2), Daphnia magna acute toxicity test (ISO 6341), Allium cepa assay, Ames test (OECD TG 471), Comet assay and YES/YAS assay. RESULTS: The wastewater ecotoxicity during one week showed no differences in separate working days, however, higher toxicity values were recorded in May compared to November. In the following study, samples from two of the five hospitals were classified as toxic, the others as non toxic. Genotoxicity has not been confirmed in any sample. In several cases, wastewater samples exhibited agonist activity to the estrogen and androgen receptors. CONCLUSION: The study demonstrated different levels of toxicity of treated hospital wastewater. Variable sensitivity of individual bioassays for tested wastewater samples was recognized. A more extensive study including proposal for improvement of hospital wastewater treatment within the Czech Republic can be recommended with the aim to decrease the discharge of toxic chemicals into the local sewage system and the environment.

000      
00000naa a2200000 a 4500
001      
bmc19044975
003      
CZ-PrNML
005      
20211208132542.0
007      
ta
008      
200109s2019 sw f 000 0|eng||
009      
AR
035    __
$a (PubMed)30796794
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sw
100    1_
$a Jírová, Gabriela $u Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, Praha - Suchdol, 165 00, Czech Republic. $7 xx0267256
245    10
$a Toxicity of wastewater from health care facilities assessed by different bioassays / $c G. Jírova, A. Vlkova, M. Wittlerova, M. Dvorakova, L. Kasparova, J. Chrz, K. Kejlová, Z. Wittlingerova, M. Zimova, B. Hosíkova, J. Jiravova, H. Kolarova,
520    9_
$a OBJECTIVES: The purpose of this study was to determine toxicity of wastewater from hospitals in the Czech Republic using traditional and alternative toxicological methods. The pilot study comprised weekly dynamics of sewage ecotoxicity of treated wastewater from one hospital in two different seasons. A detailed investigation of wastewater ecotoxicity, genotoxicity and reprotoxicity followed in five different hospitals. METHODS: The seven following bioassays were used in this study: algal growth inhibition test (ISO 8692), Vibrio fischeri test (ISO 11348-2), Daphnia magna acute toxicity test (ISO 6341), Allium cepa assay, Ames test (OECD TG 471), Comet assay and YES/YAS assay. RESULTS: The wastewater ecotoxicity during one week showed no differences in separate working days, however, higher toxicity values were recorded in May compared to November. In the following study, samples from two of the five hospitals were classified as toxic, the others as non toxic. Genotoxicity has not been confirmed in any sample. In several cases, wastewater samples exhibited agonist activity to the estrogen and androgen receptors. CONCLUSION: The study demonstrated different levels of toxicity of treated hospital wastewater. Variable sensitivity of individual bioassays for tested wastewater samples was recognized. A more extensive study including proposal for improvement of hospital wastewater treatment within the Czech Republic can be recommended with the aim to decrease the discharge of toxic chemicals into the local sewage system and the environment.
650    _2
$a Aliivibrio fischeri $x fyziologie $7 D048908
650    _2
$a zvířata $7 D000818
650    _2
$a biotest $x metody $7 D001681
650    _2
$a Chlorophyceae $x fyziologie $7 D000077105
650    _2
$a Daphnia $x fyziologie $7 D003621
650    _2
$a nemocnice $7 D006761
650    _2
$a odstraňování zdravotnického odpadu $7 D017744
650    _2
$a česneky $x fyziologie $7 D019697
650    _2
$a pilotní projekty $7 D010865
650    _2
$a odpadní voda $x analýza $x toxicita $7 D062065
650    _2
$a chemické látky znečišťující vodu $x analýza $x toxicita $7 D014874
655    _2
$a časopisecké články $7 D016428
700    1_
$a Vlkova, Alena $u Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, Praha - Suchdol, 165 00, Czech Republic.
700    1_
$a Wittlerová, Martina $u National Institute of Public Health, Centre of Health and Environment, Šrobárova 48, Praha 10, 100 42, Czech Republic. $7 xx0267253
700    1_
$a Dvorakova, Marketa $u National Institute of Public Health, Centre of Toxicology and Health Safety, Šrobárova 48, Prague, Czech Republic.
700    1_
$a Kasparova, Lucie $u National Institute of Public Health, Centre of Health and Environment, Šrobárova 48, Praha 10, 100 42, Czech Republic.
700    1_
$a Chrz, Jan, $u National Institute of Public Health, Centre of Toxicology and Health Safety, Šrobárova 48, Prague, Czech Republic. $d 1986- $7 xx0267257
700    1_
$a Kejlová, Kristina $u National Institute of Public Health, Centre of Toxicology and Health Safety, Šrobárova 48, Prague, Czech Republic.
700    1_
$a Wittlingerová, Zdeňka, $u Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, Praha - Suchdol, 165 00, Czech Republic. $d 1947- $7 mzk2005286586
700    1_
$a Zimova, Magdalena $u Faculty of Environmental Sciences, Czech University of Life Sciences Prague, Kamýcká 129, Praha - Suchdol, 165 00, Czech Republic.
700    1_
$a Hosíkova, Barbora $u Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, Olomouc, 775 15, Czech Republic.
700    1_
$a Jiravova, Jana $u Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, Olomouc, 775 15, Czech Republic.
700    1_
$a Kolarova, Hana $u Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, Olomouc, 775 15, Czech Republic.
773    0_
$w MED00168352 $t Neuro-endocrinology letters $x 0172-780X $g Roč. 39, č. 6 (2019), s. 441-453
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30796794 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20200109 $b ABA008
991    __
$a 20211208132541 $b ABA008
999    __
$a ok $b bmc $g 1483244 $s 1083648
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2019 $b 39 $c 6 $d 441-453 $e - $i 0172-780X $m Neuro-endocrinology letters $n Neuro-endocrinol. lett. $x MED00168352
LZP    __
$a Pubmed-20200109

Find record

Citation metrics

Archiving options