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Extramedullary disease in multiple myeloma - controversies and future directions
S. Sevcikova, J. Minarik, M. Stork, T. Jelinek, L. Pour, R. Hajek,
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Humans MeSH
- Multiple Myeloma complications pathology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.
Department of Internal Medicine Hematology and Oncology University Hospital Brno Brno Czech Republic
References provided by Crossref.org
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- $a Sevcikova, Sabina $u Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: sevcik@med.muni.cz.
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- $a Extramedullary disease of multiple myeloma (EM) remains a treatment challenge even in the era of new drugs. While many reports analyzing various aspects of EM have been published, mechanism of EM development has not been clarified yet. This review summarizes current knowledge about this clinical entity, including its history, diagnostics, imaging methods, incidence, prognosis, current treatment options, risk factors and known molecular mechanisms that might be involved in pathogenesis of EM.
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- $a Pour, Ludek $u Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Brno, Czech Republic. Electronic address: pour.ludek@fnbrno.cz.
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- $a Hajek, Roman $u Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine University of Ostrava, Ostrava, Czech Republic. Electronic address: roman.hajek@fno.cz.
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