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The results of interconnection of the evidence of professional exposure to genotoxic factors (regex) and cancer registry in the Czech Republic
H. Lehocká, I. Závacká, J. Vavrošová, V. Janout,
Language English Country Germany
Document type Journal Article
Grant support
R13 ES026036
NIEHS NIH HHS - United States
NLK
ProQuest Central
from 2015-10-01 to 2020-07-31
Health & Medicine (ProQuest)
from 2015-10-01 to 2020-07-31
Public Health Database (ProQuest)
from 2015-10-01 to 2020-07-31
- MeSH
- Incidence MeSH
- Humans MeSH
- Mutagens toxicity MeSH
- Neoplasms chemically induced epidemiology MeSH
- Occupational Exposure * MeSH
- Registries MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic MeSH
The aim of this study is to analyze the genotoxic risks in the Moravian-Silesian Region in the Czech Republic and assess the significance of genotoxic factors in the etiology of cancer by bringing together the Registry of Occupational Exposure to Genotoxic Factors and the Cancer Registry and compare the rate of detected cancer in persons exposed to genotoxic factors via their work in the Moravian-Silesian Region with the occurrence of cancer in the population of the Czech Republic. The results show: (a) For the monitored group (748 person) for the period 1996-2008, according to gender, was no statistically significant difference in the incidence of oncological diseases compared to the population of the Czech Republic. (b) But statistically significant difference was found in the cases of oncological diseases in groups according to % AB.C. using the Cytogenetic analysis of human peripheral lymphocytes (CAPL). The highest incidence was in the group with a higher incidence of % AB.C. High values of % AB.C. may predict the development of oncological diseases.
References provided by Crossref.org
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