-
Je něco špatně v tomto záznamu ?
Clinical experience with trans-catheter aortic valve implantation at a tertiary hospital in the Republic of Ireland
R. Tanner, B. Moran, R. Margey, G. Blake, C. McGorrian, J. Geraghty, S. Groarke, J. Boleckova, J. Hurley, A. Roy, D. Barton, D. Sugrue, IP. Casserly,
Jazyk angličtina Země Irsko
Typ dokumentu časopisecké články
Odkazy
PubMed
31197575
DOI
10.1007/s11845-019-02030-7
Knihovny.cz E-zdroje
- MeSH
- aortální chlopeň chirurgie MeSH
- aortální stenóza chirurgie MeSH
- centra terciární péče MeSH
- cévní mozková příhoda mortalita MeSH
- Kaplanův-Meierův odhad MeSH
- kohortové studie MeSH
- lidé MeSH
- prospektivní studie MeSH
- registrace MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- transkatetrální implantace aortální chlopně metody MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Irsko MeSH
INTRODUCTION: There is a paucity of published data on the clinical experience with trans-catheter aortic valve implantation (TAVI) in the Republic of Ireland. We sought to examine the clinical outcomes of patients with medium-term follow-up treated with TAVI at our institution. METHODS: A prospective TAVI registry was used to assess the baseline demographics, procedural variables and clinical outcomes of patients treated with TAVI between the inception of the programme in 2008 and November 2017. RESULTS: A total of 354 patients (mean age 80.9 ± 8.1 years, 58% male, mean STS score 6.1 ± 4.3%) were treated during the study period. Major in-hospital outcomes included in-lab death (n = 2, 0.6%), stroke (n = 8, 2.2%), device embolisation (n = 4, 1.2%), permanent pacemaker implantation (n = 22, 6.2%) and major vascular complication (n = 2, 0.6%). The median length of hospital stay was 4 days (IQR 2-8 days). The Kaplan-Meier estimate of freedom from death at 30 days and 1 year for the entire cohort was 97 ± 1% and 85.4 ± 2.3%, respectively. Trans-femoral access was associated with a significantly lower rate of death and/or stroke at 1 year compared to trans-apical access (84.9 ± 2.4% versus 60 ± 8.9%, p = 0.0005). There was no significant difference in freedom from death and/or stroke at 1 year between balloon-expandable and self-expanding valves (81.6 ± 2.6% versus 84.4 ± 7.4%, p = 0.63). CONCLUSION: This study documents low complication rates and favourable rates of survival following TAVI in a consecutive series of patients undergoing TAVI at a tertiary referral centre in the Republic of Ireland. These data support the application of this therapy in the Irish context.
Department of Cardiology Mater Misericordiae University Hospital Eccles Street Dublin 7 Ireland
- 000
- 00000naa a2200000 a 4500
- 001
- bmc20023201
- 003
- CZ-PrNML
- 005
- 20201214125455.0
- 007
- ta
- 008
- 201125s2020 ie f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s11845-019-02030-7 $2 doi
- 035 __
- $a (PubMed)31197575
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a ie
- 100 1_
- $a Tanner, Richard $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland. richard.tanner@umail.ucc.ie.
- 245 10
- $a Clinical experience with trans-catheter aortic valve implantation at a tertiary hospital in the Republic of Ireland / $c R. Tanner, B. Moran, R. Margey, G. Blake, C. McGorrian, J. Geraghty, S. Groarke, J. Boleckova, J. Hurley, A. Roy, D. Barton, D. Sugrue, IP. Casserly,
- 520 9_
- $a INTRODUCTION: There is a paucity of published data on the clinical experience with trans-catheter aortic valve implantation (TAVI) in the Republic of Ireland. We sought to examine the clinical outcomes of patients with medium-term follow-up treated with TAVI at our institution. METHODS: A prospective TAVI registry was used to assess the baseline demographics, procedural variables and clinical outcomes of patients treated with TAVI between the inception of the programme in 2008 and November 2017. RESULTS: A total of 354 patients (mean age 80.9 ± 8.1 years, 58% male, mean STS score 6.1 ± 4.3%) were treated during the study period. Major in-hospital outcomes included in-lab death (n = 2, 0.6%), stroke (n = 8, 2.2%), device embolisation (n = 4, 1.2%), permanent pacemaker implantation (n = 22, 6.2%) and major vascular complication (n = 2, 0.6%). The median length of hospital stay was 4 days (IQR 2-8 days). The Kaplan-Meier estimate of freedom from death at 30 days and 1 year for the entire cohort was 97 ± 1% and 85.4 ± 2.3%, respectively. Trans-femoral access was associated with a significantly lower rate of death and/or stroke at 1 year compared to trans-apical access (84.9 ± 2.4% versus 60 ± 8.9%, p = 0.0005). There was no significant difference in freedom from death and/or stroke at 1 year between balloon-expandable and self-expanding valves (81.6 ± 2.6% versus 84.4 ± 7.4%, p = 0.63). CONCLUSION: This study documents low complication rates and favourable rates of survival following TAVI in a consecutive series of patients undergoing TAVI at a tertiary referral centre in the Republic of Ireland. These data support the application of this therapy in the Irish context.
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a aortální chlopeň $x chirurgie $7 D001021
- 650 _2
- $a aortální stenóza $x chirurgie $7 D001024
- 650 _2
- $a kohortové studie $7 D015331
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a Kaplanův-Meierův odhad $7 D053208
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a prospektivní studie $7 D011446
- 650 _2
- $a registrace $7 D012042
- 650 _2
- $a cévní mozková příhoda $x mortalita $7 D020521
- 650 _2
- $a centra terciární péče $7 D062606
- 650 _2
- $a transkatetrální implantace aortální chlopně $x metody $7 D065467
- 650 _2
- $a výsledek terapie $7 D016896
- 651 _2
- $a Irsko $7 D007494
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Moran, Barbara $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Margey, Ronan $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Blake, Gavin $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a McGorrian, Catherine $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Geraghty, Jacqueline $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Groarke, Susan $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Boleckova, Jana $u Edwards Lifesciences AG, Prague, Czech Republic.
- 700 1_
- $a Hurley, John $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Roy, Andrew $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Barton, David $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Sugrue, Declan $u Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 700 1_
- $a Casserly, Ivan P $u Department of Cardiology, Mater Misericordiae University Hospital, Eccles Street, Dublin 7, Ireland. Mater Private Hospital, Eccles Street, Dublin 7, Ireland.
- 773 0_
- $w MED00005549 $t Irish journal of medical science $x 1863-4362 $g Roč. 189, č. 1 (2020), s. 139-148
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/31197575 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20201125 $b ABA008
- 991 __
- $a 20201214125454 $b ABA008
- 999 __
- $a ok $b bmc $g 1595520 $s 1113877
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 189 $c 1 $d 139-148 $e 20190613 $i 1863-4362 $m Irish journal of medical science $n Ir J Med Sci $x MED00005549
- LZP __
- $a Pubmed-20201125