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An overview of 25 years of research on Thermococcus kodakarensis, a genetically versatile model organism for archaeal research
N. Rashid, M. Aslam,
Language English Country United States
Document type Journal Article, Review
- MeSH
- Archaeal Proteins genetics MeSH
- Metabolic Networks and Pathways MeSH
- Thermococcus genetics growth & development metabolism MeSH
- Hot Temperature MeSH
- Research trends MeSH
- Publication type
- Journal Article MeSH
- Review MeSH
Almost 25 years have passed since the discovery of a planktonic, heterotrophic, hyperthermophilic archaeon named Thermococcus kodakarensis KOD1, previously known as Pyrococcus sp. KOD1, by Imanaka and coworkers. T. kodakarensis is one of the most studied archaeon in terms of metabolic pathways, available genomic resources, established genetic engineering techniques, reporter constructs, in vitro transcription/translation machinery, and gene expression/gene knockout systems. In addition to all these, ease of growth using various carbon sources makes it a facile archaeal model organism. Here, in this review, an attempt is made to reflect what we have learnt from this hyperthermophilic archaeon.
References provided by Crossref.org
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