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Plasmid-Mediated mcr-1 Colistin Resistance in Escherichia coli from a Black Kite in Russia
H. Tarabai, A. Valcek, I. Jamborova, SV. Vazhov, IV. Karyakin, R. Raab, I. Literak, M. Dolejska,
Language English Country United States
Document type Journal Article, Research Support, Non-U.S. Gov't
NLK
Free Medical Journals
from 1972 to 6 months ago
Freely Accessible Science Journals
from 1995 to 6 months ago
PubMed Central
from 1972 to 1 year ago
Europe PubMed Central
from 1972 to 6 months ago
Open Access Digital Library
from 1972-01-01
Open Access Digital Library
from 1972-01-01
PubMed
31307988
DOI
10.1128/aac.01266-19
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents metabolism pharmacology MeSH
- Drug Resistance, Bacterial genetics MeSH
- Raptors microbiology MeSH
- Escherichia coli drug effects enzymology genetics isolation & purification MeSH
- Escherichia coli Infections epidemiology microbiology transmission veterinary MeSH
- Colistin metabolism pharmacology MeSH
- Animal Migration MeSH
- Microbial Sensitivity Tests MeSH
- Plasmids chemistry metabolism MeSH
- Escherichia coli Proteins genetics MeSH
- Whole Genome Sequencing MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Russia MeSH
The gene mcr-1 conferring resistance to last-line antibiotic colistin has been reported globally. Here, we describe the first detection of plasmid-mediated colistin resistance in Russian wildlife, an isolate of Escherichia coli sequence type 2280 from a black kite (Milvus migrans) scavenging raptor. Whole-genome sequencing and plasmid transferability experiments revealed that mcr-1.1 was located on conjugative IncI2 plasmid pDR164 (59891 bp). Migratory black kites may contribute to the global spread of mobile colistin resistance.
LLC Sibecocenter Novosibirsk Russia
Shukshin Altai State University for Humanities and Pedagogy Biysk Russia
References provided by Crossref.org
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