Plasmid-Mediated mcr-1 Colistin Resistance in Escherichia coli from a Black Kite in Russia
Jazyk angličtina Země Spojené státy americké Médium electronic-print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
31307988
PubMed Central
PMC6709458
DOI
10.1128/aac.01266-19
PII: AAC.01266-19
Knihovny.cz E-zdroje
- Klíčová slova
- DNA sequencing, Escherichia coli, colistin, kite, landfill, plasmid, wildlife,
- MeSH
- antibakteriální látky metabolismus farmakologie MeSH
- bakteriální léková rezistence genetika MeSH
- dravci mikrobiologie MeSH
- Escherichia coli účinky léků enzymologie genetika izolace a purifikace MeSH
- infekce vyvolané Escherichia coli epidemiologie mikrobiologie přenos veterinární MeSH
- kolistin metabolismus farmakologie MeSH
- migrace zvířat MeSH
- mikrobiální testy citlivosti MeSH
- plazmidy chemie metabolismus MeSH
- proteiny z Escherichia coli genetika MeSH
- sekvenování celého genomu MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Rusko epidemiologie MeSH
- Názvy látek
- antibakteriální látky MeSH
- kolistin MeSH
- MCR-1 protein, E coli MeSH Prohlížeč
- proteiny z Escherichia coli MeSH
The gene mcr-1 conferring resistance to last-line antibiotic colistin has been reported globally. Here, we describe the first detection of plasmid-mediated colistin resistance in Russian wildlife, an isolate of Escherichia coli sequence type 2280 from a black kite (Milvus migrans) scavenging raptor. Whole-genome sequencing and plasmid transferability experiments revealed that mcr-1.1 was located on conjugative IncI2 plasmid pDR164 (59891 bp). Migratory black kites may contribute to the global spread of mobile colistin resistance.
LLC Sibecocenter Novosibirsk Russia
Shukshin Altai State University for Humanities and Pedagogy Biysk Russia
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