-
Je něco špatně v tomto záznamu ?
Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study
KK. Tsilidis, N. Papadimitriou, N. Dimou, D. Gill, SJ. Lewis, RM. Martin, N. Murphy, G. Markozannes, V. Zuber, AJ. Cross, K. Burrows, DS. Lopez, TJ. Key, RC. Travis, A. Perez-Cornago, DJ. Hunter, FJB. van Duijnhoven, D. Albanes, V. Arndt, SI....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, práce podpořená grantem
Grantová podpora
MC_UU_12013/1
Medical Research Council - United Kingdom
MC_UU_12013/2
Medical Research Council - United Kingdom
MC_UU_12013/3
Medical Research Council - United Kingdom
C18281/A19169
Cancer Research UK - United Kingdom
NLK
Free Medical Journals
od 1999 do Před 1 rokem
Freely Accessible Science Journals
od 1999 do Před 1 rokem
Open Access Digital Library
od 1999-01-01
PubMed
33740060
DOI
10.1093/ajcn/nqab003
Knihovny.cz E-zdroje
- MeSH
- běloši * MeSH
- genetická predispozice k nemoci * MeSH
- kolorektální nádory genetika MeSH
- lidé MeSH
- mendelovská randomizace * MeSH
- mikroživiny aplikace a dávkování MeSH
- potravní doplňky MeSH
- rizikové faktory MeSH
- selen krev MeSH
- studie případů a kontrol MeSH
- vitamin B 12 krev MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: The literature on associations of circulating concentrations of minerals and vitamins with risk of colorectal cancer is limited and inconsistent. Evidence from randomized controlled trials (RCTs) to support the efficacy of dietary modification or nutrient supplementation for colorectal cancer prevention is also limited. OBJECTIVES: To complement observational and RCT findings, we investigated associations of genetically predicted concentrations of 11 micronutrients (β-carotene, calcium, copper, folate, iron, magnesium, phosphorus, selenium, vitamin B-6, vitamin B-12, and zinc) with colorectal cancer risk using Mendelian randomization (MR). METHODS: Two-sample MR was conducted using 58,221 individuals with colorectal cancer and 67,694 controls from the Genetics and Epidemiology of Colorectal Cancer Consortium, Colorectal Cancer Transdisciplinary Study, and Colon Cancer Family Registry. Inverse variance-weighted MR analyses were performed with sensitivity analyses to assess the impact of potential violations of MR assumptions. RESULTS: Nominally significant associations were noted for genetically predicted iron concentration and higher risk of colon cancer [ORs per SD (ORSD): 1.08; 95% CI: 1.00, 1.17; P value = 0.05] and similarly for proximal colon cancer, and for vitamin B-12 concentration and higher risk of colorectal cancer (ORSD: 1.12; 95% CI: 1.03, 1.21; P value = 0.01) and similarly for colon cancer. A nominally significant association was also noted for genetically predicted selenium concentration and lower risk of colon cancer (ORSD: 0.98; 95% CI: 0.96, 1.00; P value = 0.05) and similarly for distal colon cancer. These associations were robust to sensitivity analyses. Nominally significant inverse associations were observed for zinc and risk of colorectal and distal colon cancers, but sensitivity analyses could not be performed. None of these findings survived correction for multiple testing. Genetically predicted concentrations of β-carotene, calcium, copper, folate, magnesium, phosphorus, and vitamin B-6 were not associated with disease risk. CONCLUSIONS: These results suggest possible causal associations of circulating iron and vitamin B-12 (positively) and selenium (inversely) with risk of colon cancer.
Behavioral and Epidemiology Research Group American Cancer Society Atlanta GA USA
Biomedicine Institute University of León León Spain
Blanquerna Faculty of Health Sciences Ramon Llull University Barcelona Spain
Broad Institute of Harvard and MIT Cambridge MA USA
Cancer Epidemiology Division Cancer Council Victoria Melbourne Victoria Australia
Center for Gastrointestinal Biology and Disease University of North Carolina Chapel Hill NC USA
Center for Public Health Genomics University of Virginia Charlottesville VA USA
Centre for Public Health Research Massey University Wellington New Zealand
Centre for Research in Epidemiology and Population Health Gustave Roussy Villejuif France
CIBER of Epidemiology and Public Health Madrid Spain
Clalit National Cancer Control Center Haifa Israel
Comprehensive Cancer Center The Ohio State University Columbus OH USA
Department of Cancer Biology and Genetics The Ohio State University Columbus OH USA
Department of Clinical Genetics Karolinska University Hospital Stockholm Sweden
Department of Clinical Sciences Faculty of Medicine University of Barcelona Barcelona Spain
Department of Community Medicine and Epidemiology Lady Davis Carmel Medical Center Haifa Israel
Department of Epidemiology Harvard TH Chan School of Public Health Harvard University Boston MA USA
Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA
Department of Epidemiology University of Iowa College of Public Health Iowa City IA USA
Department of Epidemiology University of Washington Seattle WA USA
Department of Family Medicine University of Virginia Charlottesville VA USA
Department of General Surgery University Hospital Rostock Rostock Germany
Department of Hygiene and Epidemiology University of Ioannina School of Medicine Ioannina Greece
Department of Internal Medicine University of Utah Salt Lake City UT USA
Department of Medicine Weill Cornell Medical College New York NY USA
Department of Molecular Medicine and Surgery Karolinska Institute Stockholm Sweden
Department of Nutrition Harvard TH Chan School of Public Health Harvard University Boston MA USA
Department of Pathology School of Medicine Umm Al Qura'a University Mecca Saudi Arabia
Department of Population Health Sciences University of Utah Salt Lake City UT USA
Department of Public Health and Primary Care University of Cambridge Cambridge United Kingdom
Department of Public Health Sciences School of Medicine University of California Davis Davis CA USA
Department of Radiation Sciences Oncology Unit Umeå University Umeå Sweden
Discipline of Genetics Memorial University of Newfoundland St John's Newfoundland Canada
Division of Cancer Epidemiology and Genetics National Cancer Institute NIH Bethesda MD USA
Division of Cancer Epidemiology German Cancer Research Center Heidelberg Germany
Division of Gastroenterology Massachusetts General Hospital and Harvard Medical School Boston MA USA
Division of Human Genetics Department of Internal Medicine The Ohio State University Columbus OH USA
Division of Human Nutrition and Health Wageningen University and Research Wageningen Netherlands
Division of Preventive Oncology German Cancer Research Center Heidelberg Germany
Division of Research Kaiser Permanente Northern California Oakland CA USA
Faculty of Medicine and Biomedical Center in Pilsen Charles University Pilsen Czech Republic
Formerly Department for Determinants of Chronic Diseases Bilthoven Netherlands
German Cancer Consortium Heidelberg Germany
Huntsman Cancer Institute University of Utah Salt Lake City UT USA
Institute for Health Research Kaiser Permanente Colorado Denver CO USA
Institute of Cancer Research Department of Medicine 1 Medical University Vienna Vienna Austria
Institute of Environmental Medicine Karolinska Institute Stockholm Sweden
IU Melvin and Bren Simon Cancer Center Indiana University Indianapolis IN USA
Jeonnam Regional Cancer Center Chonnam National University Hwasun Hospital Hwasun Republic of Korea
Leeds Institute of Cancer and Pathology University of Leeds Leeds United Kingdom
Medical Genetics Service University Hospital Center Nantes Nantes France
Nuffield Department of Population Health University of Oxford Oxford United Kingdom
ONCOBEL Program Bellvitge Biomedical Research Institute L'Hospitalet de Llobregat Barcelona Spain
Public Health Sciences Division Fred Hutchinson Cancer Research Center Seattle WA USA
Ruth and Bruce Rappaport Faculty of Medicine Technion Israel Institute of Technology Haifa Israel
School of Public Health University of Washington Seattle WA USA
Section of Nutrition and Metabolism International Agency for Research on Cancer Lyon France
SWOG Statistical Center Fred Hutchinson Cancer Research Center Seattle WA USA
University Medical Centre Hamburg Eppendorf University Cancer Centre Hamburg Hamburg Germany
University of Hawaii Cancer Center Honolulu HI USA
USC Norris Comprehensive Cancer Center University of Southern California Los Angeles CA USA
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21018476
- 003
- CZ-PrNML
- 005
- 20210830100100.0
- 007
- ta
- 008
- 210728s2021 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1093/ajcn/nqab003 $2 doi
- 035 __
- $a (PubMed)33740060
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Tsilidis, Konstantinos K $u Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece $u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
- 245 10
- $a Genetically predicted circulating concentrations of micronutrients and risk of colorectal cancer among individuals of European descent: a Mendelian randomization study / $c KK. Tsilidis, N. Papadimitriou, N. Dimou, D. Gill, SJ. Lewis, RM. Martin, N. Murphy, G. Markozannes, V. Zuber, AJ. Cross, K. Burrows, DS. Lopez, TJ. Key, RC. Travis, A. Perez-Cornago, DJ. Hunter, FJB. van Duijnhoven, D. Albanes, V. Arndt, SI. Berndt, S. Bézieau, DT. Bishop, J. Boehm, H. Brenner, A. Burnett-Hartman, PT. Campbell, G. Casey, S. Castellví-Bel, AT. Chan, J. Chang-Claude, A. de la Chapelle, JC. Figueiredo, SJ. Gallinger, GG. Giles, PJ. Goodman, A. Gsur, J. Hampe, H. Hampel, M. Hoffmeister, MA. Jenkins, TO. Keku, SS. Kweon, SC. Larsson, L. Le Marchand, CI. Li, L. Li, A. Lindblom, V. Martín, RL. Milne, V. Moreno, H. Nan, R. Nassir, PA. Newcomb, K. Offit, PDP. Pharoah, EA. Platz, JD. Potter, L. Qi, G. Rennert, LC. Sakoda, C. Schafmayer, ML. Slattery, L. Snetselaar, J. Schenk, SN. Thibodeau, CM. Ulrich, B. Van Guelpen, S. Harlid, K. Visvanathan, L. Vodickova, H. Wang, E. White, A. Wolk, MO. Woods, AH. Wu, W. Zheng, B. Bueno-de-Mesquita, MC. Boutron-Ruault, DJ. Hughes, P. Jakszyn, T. Kühn, D. Palli, E. Riboli, EL. Giovannucci, BL. Banbury, SB. Gruber, U. Peters, MJ. Gunter
- 520 9_
- $a BACKGROUND: The literature on associations of circulating concentrations of minerals and vitamins with risk of colorectal cancer is limited and inconsistent. Evidence from randomized controlled trials (RCTs) to support the efficacy of dietary modification or nutrient supplementation for colorectal cancer prevention is also limited. OBJECTIVES: To complement observational and RCT findings, we investigated associations of genetically predicted concentrations of 11 micronutrients (β-carotene, calcium, copper, folate, iron, magnesium, phosphorus, selenium, vitamin B-6, vitamin B-12, and zinc) with colorectal cancer risk using Mendelian randomization (MR). METHODS: Two-sample MR was conducted using 58,221 individuals with colorectal cancer and 67,694 controls from the Genetics and Epidemiology of Colorectal Cancer Consortium, Colorectal Cancer Transdisciplinary Study, and Colon Cancer Family Registry. Inverse variance-weighted MR analyses were performed with sensitivity analyses to assess the impact of potential violations of MR assumptions. RESULTS: Nominally significant associations were noted for genetically predicted iron concentration and higher risk of colon cancer [ORs per SD (ORSD): 1.08; 95% CI: 1.00, 1.17; P value = 0.05] and similarly for proximal colon cancer, and for vitamin B-12 concentration and higher risk of colorectal cancer (ORSD: 1.12; 95% CI: 1.03, 1.21; P value = 0.01) and similarly for colon cancer. A nominally significant association was also noted for genetically predicted selenium concentration and lower risk of colon cancer (ORSD: 0.98; 95% CI: 0.96, 1.00; P value = 0.05) and similarly for distal colon cancer. These associations were robust to sensitivity analyses. Nominally significant inverse associations were observed for zinc and risk of colorectal and distal colon cancers, but sensitivity analyses could not be performed. None of these findings survived correction for multiple testing. Genetically predicted concentrations of β-carotene, calcium, copper, folate, magnesium, phosphorus, and vitamin B-6 were not associated with disease risk. CONCLUSIONS: These results suggest possible causal associations of circulating iron and vitamin B-12 (positively) and selenium (inversely) with risk of colon cancer.
- 650 _2
- $a studie případů a kontrol $7 D016022
- 650 _2
- $a kolorektální nádory $x genetika $7 D015179
- 650 _2
- $a potravní doplňky $7 D019587
- 650 12
- $a běloši $7 D044465
- 650 12
- $a genetická predispozice k nemoci $7 D020022
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a mendelovská randomizace $7 D057182
- 650 _2
- $a mikroživiny $x aplikace a dávkování $7 D018977
- 650 _2
- $a rizikové faktory $7 D012307
- 650 _2
- $a selen $x krev $7 D012643
- 650 _2
- $a vitamin B 12 $x krev $7 D014805
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Papadimitriou, Nikos $u Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
- 700 1_
- $a Dimou, Niki $u Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
- 700 1_
- $a Gill, Dipender $u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
- 700 1_
- $a Lewis, Sarah J $u Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom $u Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom
- 700 1_
- $a Martin, Richard M $u Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom $u Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom $u University Hospitals Bristol National Health Service Foundation Trust National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, Bristol, United Kingdom
- 700 1_
- $a Murphy, Neil $u Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
- 700 1_
- $a Markozannes, Georgios $u Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
- 700 1_
- $a Zuber, Verena $u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom $u Medical Research Council Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
- 700 1_
- $a Cross, Amanda J $u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
- 700 1_
- $a Burrows, Kimberley $u Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom $u Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom
- 700 1_
- $a Lopez, David S $u Department of Preventive Medicine and Community Health, The University of Texas Medical Branch, Galveston, TX, USA
- 700 1_
- $a Key, Timothy J $u Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a Travis, Ruth C $u Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a Perez-Cornago, Aurora $u Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a Hunter, David J $u Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
- 700 1_
- $a van Duijnhoven, Fränzel J B $u Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, Netherlands
- 700 1_
- $a Albanes, Demetrius $u Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
- 700 1_
- $a Arndt, Volker $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
- 700 1_
- $a Berndt, Sonja I $u Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
- 700 1_
- $a Bézieau, Stéphane $u Medical Genetics Service, University Hospital Center (CHU) Nantes, Nantes, France
- 700 1_
- $a Bishop, D Timothy $u , Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, United Kingdom
- 700 1_
- $a Boehm, Juergen $u Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA $u Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA
- 700 1_
- $a Brenner, Hermann $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany $u Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany $u German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany
- 700 1_
- $a Burnett-Hartman, Andrea $u Institute for Health Research, Kaiser Permanente Colorado, Denver, CO, USA
- 700 1_
- $a Campbell, Peter T $u Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA
- 700 1_
- $a Casey, Graham $u Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
- 700 1_
- $a Castellví-Bel, Sergi $u Gastroenterology Department, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Biomedical Research Network Center for Liver and Digestive Diseases (CIBEREHD), University of Barcelona, Barcelona, Spain
- 700 1_
- $a Chan, Andrew T $u Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA $u Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA $u Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA $u Broad Institute of Harvard and MIT, Cambridge, MA, USA $u Department of Epidemiology, Harvard TH Chan School of Public Health, Harvard University, Boston, MA, USA $u Department of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Harvard University, Boston, MA, USA
- 700 1_
- $a Chang-Claude, Jenny $u Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany $u University Medical Centre Hamburg-Eppendorf, University Cancer Centre Hamburg, Hamburg, Germany
- 700 1_
- $a de la Chapelle, Albert $u Department of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, USA $u Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
- 700 1_
- $a Figueiredo, Jane C $u Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA $u Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
- 700 1_
- $a Gallinger, Steven J $u Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
- 700 1_
- $a Giles, Graham G $u Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia $u Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia $u Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia
- 700 1_
- $a Goodman, Phyllis J $u SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- 700 1_
- $a Gsur, Andrea $u Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
- 700 1_
- $a Hampe, Jochen $u Department of Medicine I, University Hospital Dresden, Dresden University of Technology (TU Dresden), Dresden, Germany
- 700 1_
- $a Hampel, Heather $u Division of Human Genetics, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA
- 700 1_
- $a Hoffmeister, Michael $u Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
- 700 1_
- $a Jenkins, Mark A $u Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia
- 700 1_
- $a Keku, Temitope O $u Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC, USA
- 700 1_
- $a Kweon, Sun-Seog $u Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea $u Jeonnam Regional Cancer Center, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea
- 700 1_
- $a Larsson, Susanna C $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
- 700 1_
- $a Le Marchand, Loic $u University of Hawaii Cancer Center, Honolulu, HI, USA
- 700 1_
- $a Li, Christopher I $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- 700 1_
- $a Li, Li $u Department of Family Medicine, University of Virginia, Charlottesville, VA, USA
- 700 1_
- $a Lindblom, Annika $u Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden $u Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
- 700 1_
- $a Martín, Vicente $u CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain $u Biomedicine Institute (IBIOMED), University of León, León, Spain
- 700 1_
- $a Milne, Roger L $u Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia $u Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia $u Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia
- 700 1_
- $a Moreno, Victor $u CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain $u Oncology Data Analytics Program, Catalan Institute of Oncology-Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain $u Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain $u ONCOBEL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain
- 700 1_
- $a Nan, Hongmei $u Department of Epidemiology, Richard M Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA $u IU Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA
- 700 1_
- $a Nassir, Rami $u Department of Pathology, School of Medicine, Umm Al-Qura'a University, Mecca, Saudi Arabia
- 700 1_
- $a Newcomb, Polly A $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA $u School of Public Health, University of Washington, Seattle, WA, USA
- 700 1_
- $a Offit, Kenneth $u Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA $u Department of Medicine, Weill Cornell Medical College, New York, NY, USA
- 700 1_
- $a Pharoah, Paul D P $u Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
- 700 1_
- $a Platz, Elizabeth A $u Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
- 700 1_
- $a Potter, John D $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA $u Centre for Public Health Research, Massey University, Wellington, New Zealand
- 700 1_
- $a Qi, Lihong $u Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, CA, USA
- 700 1_
- $a Rennert, Gad $u Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel $u Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel $u Clalit National Cancer Control Center, Haifa, Israel
- 700 1_
- $a Sakoda, Lori C $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA $u Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA
- 700 1_
- $a Schafmayer, Clemens $u Department of General Surgery, University Hospital Rostock, Rostock, Germany
- 700 1_
- $a Slattery, Martha L $u Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA
- 700 1_
- $a Snetselaar, Linda $u Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA
- 700 1_
- $a Schenk, Jeanette $u SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- 700 1_
- $a Thibodeau, Stephen N $u Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
- 700 1_
- $a Ulrich, Cornelia M $u Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA $u Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA
- 700 1_
- $a Van Guelpen, Bethany $u Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden
- 700 1_
- $a Harlid, Sophia $u Department of Radiation Sciences, Oncology Unit, Umeå University, Umeå, Sweden
- 700 1_
- $a Visvanathan, Kala $u Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
- 700 1_
- $a Vodickova, Ludmila $u Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic $u Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic $u Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic
- 700 1_
- $a Wang, Hansong $u University of Hawaii Cancer Center, Honolulu, HI, USA
- 700 1_
- $a White, Emily $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA $u Department of Epidemiology, University of Washington, Seattle, WA, USA
- 700 1_
- $a Wolk, Alicja $u Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
- 700 1_
- $a Woods, Michael O $u Discipline of Genetics, Memorial University of Newfoundland, St. John's, Newfoundland, Canada
- 700 1_
- $a Wu, Anna H $u Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
- 700 1_
- $a Zheng, Wei $u Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA
- 700 1_
- $a Bueno-de-Mesquita, Bas $u Formerly, Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands
- 700 1_
- $a Boutron-Ruault, Marie-Christine $u Faculty of Medicine, CESP, University of Paris-Sud, Faculty of Medicine UVSQ, INSERM, University of Paris-Saclay, Villejuif, France $u Centre for Research in Epidemiology and Population Health (CESP), Gustave Roussy, Villejuif, France
- 700 1_
- $a Hughes, David J $u Cancer Biology and Therapeutics Group, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
- 700 1_
- $a Jakszyn, Paula $u Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology- Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain $u Blanquerna Faculty of Health Sciences, Ramon Llull University, Barcelona, Spain
- 700 1_
- $a Kühn, Tilman $u Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany
- 700 1_
- $a Palli, Domenico $u Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network-ISPRO, Florence, Italy
- 700 1_
- $a Riboli, Elio $u Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
- 700 1_
- $a Giovannucci, Edward L $u Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA $u Department of Epidemiology, Harvard TH Chan School of Public Health, Harvard University, Boston, MA, USA $u Department of Nutrition, Harvard TH Chan School of Public Health, Harvard University, Boston, MA, USA
- 700 1_
- $a Banbury, Barbara L $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- 700 1_
- $a Gruber, Stephen B $u Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA $u USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
- 700 1_
- $a Peters, Ulrike $u Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA $u Department of Epidemiology, University of Washington, Seattle, WA, USA
- 700 1_
- $a Gunter, Marc J $u Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France
- 773 0_
- $w MED00000237 $t The American journal of clinical nutrition $x 1938-3207 $g Roč. 113, č. 6 (2021), s. 1490-1502
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/33740060 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210728 $b ABA008
- 991 __
- $a 20210830100100 $b ABA008
- 999 __
- $a ok $b bmc $g 1689547 $s 1138922
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2021 $b 113 $c 6 $d 1490-1502 $e 20210601 $i 1938-3207 $m The American journal of clinical nutrition $n Am J Clin Nutr $x MED00000237
- GRA __
- $a MC_UU_12013/1 $p Medical Research Council $2 United Kingdom
- GRA __
- $a MC_UU_12013/2 $p Medical Research Council $2 United Kingdom
- GRA __
- $a MC_UU_12013/3 $p Medical Research Council $2 United Kingdom
- GRA __
- $a C18281/A19169 $p Cancer Research UK $2 United Kingdom
- LZP __
- $a Pubmed-20210728
