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Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey
KS. Frederiksen, TR. Nielsen, I. Appollonio, BB. Andersen, M. Riverol, M. Boada, M. Ceccaldi, B. Dubois, S. Engelborghs, L. Frölich, L. Hausner, A. Gabelle, T. Gabryelewicz, T. Grimmer, B. Hanseeuw, J. Hort, J. Hugon, V. Jelic, A. Koivisto, MG....
Language English Country Great Britain
Document type Journal Article
PubMed
32896040
DOI
10.1002/gps.5427
Knihovny.cz E-resources
- MeSH
- Alzheimer Disease * diagnosis MeSH
- Biomarkers MeSH
- Cognitive Dysfunction * diagnosis MeSH
- Humans MeSH
- Follow-Up Studies MeSH
- Counseling MeSH
- Disease Progression MeSH
- Sensitivity and Specificity MeSH
- Disclosure MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Europe MeSH
OBJECTIVES: Mild cognitive impairment (MCI) is associated with an increased risk of further cognitive decline, partly depending on demographics and biomarker status. The aim of the present study was to survey the clinical practices of physicians in terms of biomarker counseling, management, and follow-up in European expert centers diagnosing patients with MCI. METHODS: An online email survey was distributed to physicians affiliated with European Alzheimer's disease Consortium centers (Northern Europe: 10 centers; Eastern and Central Europe: 9 centers; and Southern Europe: 15 centers) with questions on attitudes toward biomarkers and biomarker counseling in MCI and dementia. This included postbiomarker counseling and the process of diagnostic disclosure of MCI, as well as treatment and follow-up in MCI. RESULTS: The response rate for the survey was 80.9% (34 of 42 centers) across 20 countries. A large majority of physicians had access to biomarkers and found them useful. Pre- and postbiomarker counseling varied across centers, as did practices for referral to support groups and advice on preventive strategies. Less than half reported discussing driving and advance care planning with patients with MCI. CONCLUSIONS: The variability in clinical practices across centers calls for better biomarker counseling and better training to improve communication skills. Future initiatives should address the importance of communicating preventive strategies and advance planning.
Ageing Epidemiology Research Unit School of Public Health Imperial College London London UK
Center for Cognitive Impairments University Medical Center Ljubljana Ljubljana Slovenia
Center of Cognitive Neurology Lariboisière Hospital Paris University of Paris Paris France
Clinic for Cognitive Disorders Theme Aging Karolinska University Hospital Huddinge Stockholm Sweden
Department of Neurodegenerative Disorders Mossakowski Medical Research Centre PAN Warsaw Poland
Department of Neurology Clinica Universidad de Navarra University of Navarra Madrid Spain
Department of Neurology Columbia University Medical Center New York USA
Department of Neurology Dokuz Eylül University Medical School Izmir Turkey
Department of Neurology UH Alexandrovska Sofia Bulgaria
Department of Neurology University of Eastern Finland Kuopio University Hospital Kuopio Finland
Department of Neuroscience University of Genoa Genoa Italy
Department of Neurosciences Dokuz Eylül University Medical School Izmir Turkey
Excellence Memory Clinic and Longevity Medicine Ana Aslan International Foundation Bucharest Romania
Faculdade de Medicina da Universidade de Lisboa Lisbon Portugal
Faculty of Medicine University of Coimbra Coimbra Portugal
German Center for Neurodegenerative Disorders Munich Munich Germany
IRCCS Ospedale Policlinico San Martino Genova Italy
Lille 2 University of Health and Law Pôle de Neurologie Lille France
Memory Clinic Clinical Research Center Toulouse University Hospital Toulouse France
Memory Clinic St James's Hospital Dublin Ireland
Munich Cluster for Systems Neurology Munich Germany
Networking Research Center on Neurodegenerative Diseases Instituto de Salud Carlos 3 Madrid Spain
Neurology Department Centro Hospitalar e Universitário de Coimbra Coimbra Portugal
Neurology Department Hospital de la Santa Creu i Sant Pau Barcelona Spain
Neuroprogressive Disorders and Dementia Network Ninewells Hospital Dundee Scotland
Servicio de geriatria Hospital Universitario Ramon y Cajal Madrid Spain
References provided by Crossref.org
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