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Molecular characterization of alcohol-ether extract from bovine tissue

Klara Kubelkova, Martin Hubalek, Pavel Rehulka, Helena Rehulkova, David Friedecky, Jitka Zakova, Ales Macela

. 2021 ; 90 (3) : 120-136. [pub] 20210903

Jazyk angličtina Země Česko

Perzistentní odkaz   https://www.medvik.cz/link/bmc21023812

It is usual for information to be unavailable regarding the molecular composition of extracts from herbs or animal tissues that are popular in folk medicine. Here, we present analysis of the alcohol-ether extract from bovine tissue analogous to the basic substance used in such commercial products as Retisin, Imuregen, Actovegin, and Solcoseryl. The tested extract contains a whole spectrum of free amino acids, small proteins and oligopeptides of molecular weight up to 10 kDa, various nucleotides, and a small amount of phospholipids. Among the molecules that can explain some biological activities of the extract were identified those of taurine (2-aminoethanesulfonic acid, a derivative of the amino acid cysteine), several defensins, and bactericidal hemoglobin fragments known as hemocidins. All those molecules identified are natural components of bovine tissues, and a substantial number of them might be biologically active in vivo. Others are sources of readily available nutrients.

Citace poskytuje Crossref.org

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