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Aortic valve replacement: validation of the Toronto Aortic Stenosis Quality of Life Questionnaire
D. Frank, S. Kennon, N. Bonaros, L. Stastny, M. Romano, T. Lefèvre, C. Di Mario, P. Stefàno, F. Ribichini, D. Himbert, M. Urena-Alcazar, J. Salgado-Fernandez, JJC. Castillo, B. Garcia Del Blanco, C. Deutsch, L. Sykorova, J. Kurucova, M. Thoenes,...
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
Directory of Open Access Journals
od 2014
Free Medical Journals
od 2014
PubMed Central
od 2015
Europe PubMed Central
od 2015
ProQuest Central
od 2014-09-01
Open Access Digital Library
od 2014-09-01
Open Access Digital Library
od 2014-01-01
Health & Medicine (ProQuest)
od 2014-09-01
Wiley-Blackwell Open Access Titles
od 2014
ROAD: Directory of Open Access Scholarly Resources
od 2014
PubMed
33207035
DOI
10.1002/ehf2.12961
Knihovny.cz E-zdroje
- MeSH
- aortální chlopeň MeSH
- aortální stenóza * diagnóza chirurgie MeSH
- kvalita života * MeSH
- lidé MeSH
- prospektivní studie MeSH
- průzkumy a dotazníky MeSH
- reprodukovatelnost výsledků MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Evropa MeSH
- Kanada MeSH
AIMS: There is no quality of life tool specifically developed for patients with severe aortic stenosis (AS) to assess how this chronic condition and its treatment affect patients. The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) has been developed to overcome this gap. The results of the validation of the TASQ in patients undergoing treatment for severe AS are presented. METHODS AND RESULTS: Prospective study at 10 centres in Europe and Canada, which enrolled 274 patients with severe symptomatic AS undergoing surgical or transcatheter aortic valve replacement. Mean TASQ score at baseline was 71.2 points and increased to 88.9 three months after aortic valve implantation (P < 0.001). Increases were seen for the emotional impact (32.0 to 39.0; P < 0.001), physical limitations (14.8 to 22.0; P < 0.001), and physical symptoms (8.5 vs. 11.0; P < 0.001) domains. Internal consistency was good/excellent for overall TASQ score (α = 0.891) and for the physical limitation, emotional impact, and social limitation domains (α = 0.815-0.950). Test-retest reliability was excellent or strong for the overall TASQ (intraclass correlation coefficient of 0.883) and for the physical symptoms, physical limitation, emotional impact, and social limitation domains (intraclass correlation coefficient of 0.791-0.895). Responsiveness was medium overall (Cohen's d = 0.637) and medium/large for physical symptoms, emotional impact, and physical limitations (0.661-0.812). Sensitivity to change was significant for physical symptoms, physical limitations (both P < 0.001), emotional impact (P = 0.003), and social limitations (P = 0.038). CONCLUSIONS: The TASQ is a new, brief, self-administered, and clinically relevant health-specific tool to measure changes in quality of life in patients with AS undergoing an intervention.
Department of Cardiac Surgery Innsbruck Medical University Innsbruck Austria
Department of Cardiology Barts Heart Centre St Bartholomew's Hospital London UK
Department of Cardiology Bichat Claude Bernard Hospital Paris France
Department of Cardiology Department of Cardiovascular Surgery Hospital Juan Canalejo Coruña Spain
Department of Cardiology Hospital Vall d'Hebron CIBER CV Barcelona Spain
Department of Psychiatry University Health Network Toronto Canada
Division of Cardiology Department of Medicine University of Verona Verona Italy
Edwards Lifesciences Nyon Switzerland
Edwards Lifesciences Prague Czech Republic
Institute for Pharmacology and Preventive Medicine Cloppenburg Germany
Citace poskytuje Crossref.org
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- $a AIMS: There is no quality of life tool specifically developed for patients with severe aortic stenosis (AS) to assess how this chronic condition and its treatment affect patients. The Toronto Aortic Stenosis Quality of Life Questionnaire (TASQ) has been developed to overcome this gap. The results of the validation of the TASQ in patients undergoing treatment for severe AS are presented. METHODS AND RESULTS: Prospective study at 10 centres in Europe and Canada, which enrolled 274 patients with severe symptomatic AS undergoing surgical or transcatheter aortic valve replacement. Mean TASQ score at baseline was 71.2 points and increased to 88.9 three months after aortic valve implantation (P < 0.001). Increases were seen for the emotional impact (32.0 to 39.0; P < 0.001), physical limitations (14.8 to 22.0; P < 0.001), and physical symptoms (8.5 vs. 11.0; P < 0.001) domains. Internal consistency was good/excellent for overall TASQ score (α = 0.891) and for the physical limitation, emotional impact, and social limitation domains (α = 0.815-0.950). Test-retest reliability was excellent or strong for the overall TASQ (intraclass correlation coefficient of 0.883) and for the physical symptoms, physical limitation, emotional impact, and social limitation domains (intraclass correlation coefficient of 0.791-0.895). Responsiveness was medium overall (Cohen's d = 0.637) and medium/large for physical symptoms, emotional impact, and physical limitations (0.661-0.812). Sensitivity to change was significant for physical symptoms, physical limitations (both P < 0.001), emotional impact (P = 0.003), and social limitations (P = 0.038). CONCLUSIONS: The TASQ is a new, brief, self-administered, and clinically relevant health-specific tool to measure changes in quality of life in patients with AS undergoing an intervention.
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