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Je něco špatně v tomto záznamu ?
Do stereoisomers of homocysteic acid exhibit different convulsant action in immature rats
P. Mareš, J. Folbergrová, R. Haugvicová, H. Kubová
Jazyk angličtina Země Česko
Typ dokumentu časopisecké články
NLK
Directory of Open Access Journals
od 1991
Free Medical Journals
od 1998
ProQuest Central
od 2005-01-01
Medline Complete (EBSCOhost)
od 2006-01-01
Nursing & Allied Health Database (ProQuest)
od 2005-01-01
Health & Medicine (ProQuest)
od 2005-01-01
ROAD: Directory of Open Access Scholarly Resources
od 1998
- MeSH
- 2-amino-5-fosfonovalerát analogy a deriváty MeSH
- AMPA receptory antagonisté a inhibitory MeSH
- benzodiazepiny MeSH
- chinoxaliny MeSH
- dizocilpinmaleát MeSH
- homocystein analogy a deriváty chemie toxicita MeSH
- potkani Wistar MeSH
- receptory N-methyl-D-aspartátu antagonisté a inhibitory MeSH
- stereoizomerie MeSH
- záchvaty chemicky indukované MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
Mechanism of ictogenesis of D- and L-stereroisomers of homocysteic acid was studied in 12-day-old rats by means of antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. There was no qualitative difference between the two stereoisomers in generation of emprosthotonic (flexion) as well as generalized tonic-clonic seizures. Moderate differences were observed in the first, nonconvulsive effects of the two isomers. As generation of the two types of seizures is concerned, NMDA and AMPA participate in generalized tonic-clonic seizures whereas NMDA receptors play a dominant role in generation of flexion seizures.
Citace poskytuje Crossref.org
Literatura
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