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Influenza and pneumococcus vaccination rates in pediatric dialysis patients in Europe: recommendations vs reality A European Pediatric Dialysis Working Group and European Society for Pediatric Nephrology Dialysis Working Group stud
YÖ. Atikel, SA. Bakkaloğlu, F. Paglialonga, CJ. Stefanidis, V. Askiti, E. Vidal, G. Ariceta, E. Melek, E. Verrina, N. Printza, K. Vondrak, A. Zurowska, I. Zagozdzon, M. Ekim, EN. Özmert, S. Dufek, A. Jankauskiene, CP. Schmitt, E. Levai, JV....
Jazyk angličtina Země Turecko
Typ dokumentu časopisecké články
PubMed
33535736
DOI
10.3906/sag-2012-26
Knihovny.cz E-zdroje
- MeSH
- chřipka lidská prevence a kontrola MeSH
- chronická renální insuficience komplikace terapie MeSH
- dialýza ledvin metody MeSH
- dítě MeSH
- imunizace statistika a číselné údaje MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- nefrologie * normy MeSH
- pediatrie MeSH
- pneumokokové vakcíny aplikace a dávkování MeSH
- předškolní dítě MeSH
- protilátky analýza MeSH
- retrospektivní studie MeSH
- společnosti lékařské MeSH
- Streptococcus pneumoniae MeSH
- vakcinace statistika a číselné údaje MeSH
- vakcíny proti chřipce aplikace a dávkování MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- Publikační typ
- časopisecké články MeSH
Background/aim: Children on dialysis are under increased risk of influenza and invasive pneumococcal disease. Although vaccination against these microorganisms are recommended in dialysis patients and despite the fact that these vaccines can reduce disease burden and rates of hospitalization due to infection, vaccination rates are below expected and desired. We aimed to evaluate influenza and pneumococcal vaccination and infection rates in European pediatric dialysis centers. Materials and methods: In 16 centers from 11 countries, 357 pediatric dialysis patients were evaluated retrospectively during 1 year of observation period between 01.01.2014 and 01.01.2015. Results: In all centers, vaccination policy included immunization of dialysis patients with inactive influenza vaccine and pneumococcal conjugate vaccine (PCV). Fifty percent of the centers recommended pneumococcal polysaccharide vaccine following routine PCV series. A significantly higher pneumococcal vaccination rate (43.9%) was seen in peritoneal dialysis (PD) patients compared to those on hemodialysis (HD) (32.9%) (p = 0.035), while the rates for influenza were similar (42.4% and 46.1% respectively, p = 0.496). Among all dialysis patients, 2.2% (n = 8) developed pneumonia and 6.4% (n = 23) was infected by Influenza. Pneumococcic pneumonia rate was 5% for 140 patients who received antipneumococcal vaccine, while only one pneumonia episode was recorded out of 217 unvaccinated patients (p = 0.007). The influenza virus infection rates were similar for patients vaccinated and nonvaccinated (7 % and 6 %, respectively). Conclusions: Although influenza and pneumococcal vaccines are highly recommended in pediatric dialysis patients, vaccination rates were lower than expected. Pneumococcal vaccination rates were higher in PD compared to the patients on HD. The rate of children with influenza infection was higher than pneumonia. The efficacy of influenza and pneumococcal vaccines was highlighted by the low infection rates. Higher pneumonia rates in patients vaccinated against pneumococcus compared to unvaccinated ones might be due to coexisting risk factors.
1st Pediatric Department Faculty of Medicine Aristotle University of Thessaloniki Thessaloníki Greec
Department of Pediatric Nephrology A and P Kyriakou Children's Hospital Athens Greec
Department of Pediatric Nephrology Cerrahpaşa Medical School İstanbul Turke
Department of Pediatric Nephrology Faculty of Medicine Ankara University Ankara Turke
Department of Pediatric Nephrology Faculty of Medicine Çukurova University Adana Turke
Department of Pediatric Nephrology Faculty of Medicine Gazi University Ankara Turke
Department of Pediatric Nephrology Faculty of Medicine Padova University Padova Ital
Department of Pediatric Nephrology Faculty of Medicine University of Helsinki Helsinki Finlan
Department of Pediatric Nephrology Great Ormond Street Hospital for Children London U
Department of Pediatric Nephrology Hopital de Hautepierre Strasbourg Franc
Department of Pediatric Nephrology KfH Children's Kidney Center Marburg German
Department of Pediatric Nephrology Medical University of Vienna Vienna Austri
Department of Pediatric Nephrology Mitera Children's Hospital Athens Greec
Department of Pediatric Nephrology University Hospital Vall d' Hebron Barcelona Spai
Department of Pediatric Nephrology Utoped Universitair Ziekenhuis Gent Ghent Belgiu
Department of Pediatrics Nephrology and Hypertension Medical University of Gdansk Gdansk Polan
Department of Social Pediatrics Faculty of Medicine Hacettepe University Ankara Turke
Dialysis Unit Department of Pediatrics IRCCS Istituto Giannina Gaslini Genoa Ital
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Ital
Pediatric Center Institute of Clinical Medicine Vilnius University Vilnius Lithuani
Pediatric Nephrology Center for Pediatric and Adolescent Medicine Heidelberg German
Citace poskytuje Crossref.org
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