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Nanotechnology-Abetted Astaxanthin Formulations in Multimodel Therapeutic and Biomedical Applications
Z. Jafari, A. Bigham, S. Sadeghi, SM. Dehdashti, N. Rabiee, A. Abedivash, M. Bagherzadeh, B. Nasseri, H. Karimi-Maleh, E. Sharifi, RS. Varma, P. Makvandi
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, přehledy
- MeSH
- lékové transportní systémy * MeSH
- lidé MeSH
- nanostruktury aplikace a dávkování chemie MeSH
- nanotechnologie metody MeSH
- preventivní lékařství * MeSH
- xanthofyly aplikace a dávkování chemie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
Astaxanthin (AXT) is one of the most important fat-soluble carotenoids that have abundant and diverse therapeutic applications namely in liver disease, cardiovascular disease, cancer treatment, protection of the nervous system, protection of the skin and eyes against UV radiation, and boosting the immune system. However, due to its intrinsic reactivity, it is chemically unstable, and therefore, the design and production processes for this compound need to be precisely formulated. Nanoencapsulation is widely applied to protect AXT against degradation during digestion and storage, thus improving its physicochemical properties and therapeutic effects. Nanocarriers are delivery systems with many advantages─ease of surface modification, biocompatibility, and targeted drug delivery and release. This review discusses the technological advancement in nanocarriers for the delivery of AXT through the brain, eyes, and skin, with emphasis on the benefits, limitations, and efficiency in practice.
Department of Chemistry Sharif University of Technology 11155 9161 Tehran Iran
Department of Physics Sharif University of Technology 11155 9161 Tehran Iran
School of Engineering Macquarie University Sydney New South Wales 2109 Australia
Citace poskytuje Crossref.org
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- $a Astaxanthin (AXT) is one of the most important fat-soluble carotenoids that have abundant and diverse therapeutic applications namely in liver disease, cardiovascular disease, cancer treatment, protection of the nervous system, protection of the skin and eyes against UV radiation, and boosting the immune system. However, due to its intrinsic reactivity, it is chemically unstable, and therefore, the design and production processes for this compound need to be precisely formulated. Nanoencapsulation is widely applied to protect AXT against degradation during digestion and storage, thus improving its physicochemical properties and therapeutic effects. Nanocarriers are delivery systems with many advantages─ease of surface modification, biocompatibility, and targeted drug delivery and release. This review discusses the technological advancement in nanocarriers for the delivery of AXT through the brain, eyes, and skin, with emphasis on the benefits, limitations, and efficiency in practice.
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