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Bioink: a 3D-bioprinting tool for anticancer drug discovery and cancer management
AP. Tiwari, ND. Thorat, S. Pricl, RM. Patil, S. Rohiwal, H. Townley
Language English Country Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Printing, Three-Dimensional * MeSH
- Bioprinting * MeSH
- Humans MeSH
- Neoplasms drug therapy MeSH
- Drug Discovery * MeSH
- Antineoplastic Agents therapeutic use MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
'Bioinks' are important tools for the fabrication of artificial living-tissue constructs that are able to mimic all properties of native tissues via 3D bioprinting technologies. Bioinks are most commonly made by incorporating live cells of interest within a natural or synthetic biocompatible polymeric matrix. In oncology research, the ability to recreate a tumor microenvironment (TME) using by 3D bioprinting constitutes a promising approach for drug development, screening, and in vitro cancer modeling. Here, we review the different types of bioink used for 3D bioprinting, with a focus on its application in cancer management. In addition, we consider the fabrication of bioink using customized materials/cells and their properties in the field of cancer drug discovery.
References provided by Crossref.org
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