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Efficacy of Prednisone in Children with Acute Nonspecific Mesenteric Lymphadenitis: A Pilot Study
M. Pavlovic, Z. Rokvic, K. Berenji
Language English Country Czech Republic
Document type Journal Article
Digital library NLK
Source
NLK
Directory of Open Access Journals
from 1997
Free Medical Journals
from 1997
Open Access Digital Library
from 1997-01-01
Medline Complete (EBSCOhost)
from 2012-06-01
ROAD: Directory of Open Access Scholarly Resources
from 1997
- MeSH
- Abdomen, Acute * etiology MeSH
- Abdominal Pain diagnosis drug therapy etiology MeSH
- Child MeSH
- Humans MeSH
- Mesenteric Lymphadenitis * complications diagnosis MeSH
- Pilot Projects MeSH
- Prednisone therapeutic use MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
BACKGROUND: Acute nonspecific mesenteric lymphadenitis (ANML) is a common cause of acute abdominal pain in children with no specific treatment. METHODS: A total of 13 patients (6 boys, 7 girls) aged 7.3 (5-13.5) years with severe acute abdominal pain were evaluated using ultrasonography and laboratory tests to establish the diagnosis of ANML. They were treated with prednisone 1 mg/kg (max 40 mg daily) for a maximum of 5 days. The intensity of abdominal pain was evaluated before and after treatment using a numeric rating scale. RESULTS: All patients had pain scores above 6/10 before, and below 4/10 after treatment with prednisone. Intensity of abdominal pain after treatment for 1-5 days decreased significantly (p < 0.001), with no recurrence at follow-up within 3 months. All other pre-existing signs and symptoms, such as nausea, vomiting, anorexia, fever, diarrhea, and constipation were found to disappear with no adverse effects of corticosteroid therapy. CONCLUSION: These results suggest that the treatment with prednisone in selective patients with ANML can reduce the duration of abdominal pain.
Children's Ambulatory Care Center Subotica Serbia
Department of Diagnostic Imaging General Hospital Subotica Serbia
Department of Hygiene and Human Ecology Public Health Institute Subotica Serbia
References provided by Crossref.org
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