-
Something wrong with this record ?
Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry
Y. Bohbot, G. Habib, C. Laroche, E. Stöhr, C. Chirouze, M. Hernandez-Meneses, M. Melissopoulou, B. Mutlu, V. Scheggi, L. Branco, C. Olmos, G. Reyes, M. Pazdernik, B. Iung, R. Sow, M. Mirocevic, P. Lancellotti, C. Tribouilloy, EORP EURO-ENDO...
Language English Country England, Great Britain
Document type Journal Article, Research Support, Non-U.S. Gov't, Comment
NLK
Medline Complete (EBSCOhost)
from 2000-03-01 to 1 year ago
Wiley Free Content
from 1999 to 1 year ago
PubMed
35508915
DOI
10.1002/ejhf.2525
Knihovny.cz E-resources
- MeSH
- Endocarditis, Bacterial * complications epidemiology MeSH
- Endocarditis * complications epidemiology MeSH
- Middle Aged MeSH
- Humans MeSH
- Hospital Mortality MeSH
- Prospective Studies MeSH
- Registries MeSH
- Retrospective Studies MeSH
- Heart Failure * complications epidemiology MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Comment MeSH
- Research Support, Non-U.S. Gov't MeSH
AIMS: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. METHODS AND RESULTS: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p ≤ 0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73-3.24; p < 0.001) and 1-year mortality (hazard ratio [HR] 1.69, 95% CI 1.39-2.05; p < 0.001) after adjustment for established outcome predictors, including early surgery, or after propensity matching for age, sex, and comorbidity (n = 618 [88.5%] for each group, both p < 0.001). Early surgery, performed on 49% of these patients with IE complicated by CHF, remained associated with a substantial reduction in 30-day mortality following multivariable analysis, after adjustment for age, sex, Charlson comorbidity index, cerebrovascular accident, Staphylococcus aureus IE, streptococcal IE, uncontrolled infection, vegetation size >10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20-0.41; p < 0.001). CONCLUSION: Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mortality but is performed on only approximately half of patients with CHF, mainly because of a surgical risk considered prohibitive.
Aix Marseille University IRD AP HM MEPHI IHU Mediterranean Infection Marseille France
Cardiology Department Bichat Hospital AP HP Paris France
Department of Cardiology Amiens University Hospital Amiens France
Department of Cardiology CHR Citadelle Liège Belgium
Department of Cardiology Clinical Centre of Montenegro Podgorica Montenegro
Department of Cardiology Heart Center University of Bonn Bonn Germany
Department of Cardiology IKEM Prague Czech Republic
Department of cardiology Luxembourg Hospital Centre Luxembourg Luxembourg
Department of Cardiology Santa Marta Hospital Lisbon Portugal
Maladies Infectieuses et Tropicales Centre Hospitalier Régional Universitaire Besançon France
UMR CNRS 6249 Chrono Environnement Université Bourgogne Franche Comté Besançon France
UR UPJV 7517 Jules Verne University of Picardie Amiens France
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc22025310
- 003
- CZ-PrNML
- 005
- 20221031100131.0
- 007
- ta
- 008
- 221017s2022 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1002/ejhf.2525 $2 doi
- 035 __
- $a (PubMed)35508915
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Bohbot, Yohann $u Department of Cardiology, Amiens University Hospital, Amiens, France $u UR UPJV 7517, Jules Verne University of Picardie, Amiens, France $1 https://orcid.org/0000000226959848
- 245 10
- $a Characteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry / $c Y. Bohbot, G. Habib, C. Laroche, E. Stöhr, C. Chirouze, M. Hernandez-Meneses, M. Melissopoulou, B. Mutlu, V. Scheggi, L. Branco, C. Olmos, G. Reyes, M. Pazdernik, B. Iung, R. Sow, M. Mirocevic, P. Lancellotti, C. Tribouilloy, EORP EURO-ENDO Registry Investigators Group
- 520 9_
- $a AIMS: To evaluate the current management and survival of patients with left-sided infective endocarditis (IE) complicated by congestive heart failure (CHF) in the ESC-EORP European Endocarditis (EURO-ENDO) registry. METHODS AND RESULTS: Among the 3116 patients enrolled in this prospective registry, 2449 (mean age: 60 years, 69% male) with left-sided (native or prosthetic) IE were included in this study. Patients with CHF (n = 698, 28.5%) were older, with more comorbidity and more severe valvular damage (mitro-aortic involvement, vegetations >10 mm and severe regurgitation/new prosthesis dehiscence) than those without CHF (all p ≤ 0.019). Patients with CHF experienced higher 30-day and 1-year mortality than those without (20.5% vs. 9.0% and 36.1% vs. 19.3%, respectively) and CHF remained strongly associated with 30-day (odds ratio[OR] 2.37, 95% confidence interval [CI] [1.73-3.24; p < 0.001) and 1-year mortality (hazard ratio [HR] 1.69, 95% CI 1.39-2.05; p < 0.001) after adjustment for established outcome predictors, including early surgery, or after propensity matching for age, sex, and comorbidity (n = 618 [88.5%] for each group, both p < 0.001). Early surgery, performed on 49% of these patients with IE complicated by CHF, remained associated with a substantial reduction in 30-day mortality following multivariable analysis, after adjustment for age, sex, Charlson comorbidity index, cerebrovascular accident, Staphylococcus aureus IE, streptococcal IE, uncontrolled infection, vegetation size >10 mm, severe valvular regurgitation and/or new prosthetic dehiscence, perivalvular complication, and prosthetic IE (OR 0.22, 95% CI 0.12-0.38; p < 0.001) and in 1-year mortality (HR 0.29, 95% CI 0.20-0.41; p < 0.001). CONCLUSION: Congestive heart failure is common in left-sided IE and is associated with older age, greater comorbidity, more advanced lesions, and markedly higher 30-day and 1-year mortality. Early surgery is strongly associated with lower mortality but is performed on only approximately half of patients with CHF, mainly because of a surgical risk considered prohibitive.
- 650 12
- $a endokarditida $x komplikace $x epidemiologie $7 D004696
- 650 12
- $a bakteriální endokarditida $x komplikace $x epidemiologie $7 D004697
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 12
- $a srdeční selhání $x komplikace $x epidemiologie $7 D006333
- 650 _2
- $a mortalita v nemocnicích $7 D017052
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a prospektivní studie $7 D011446
- 650 _2
- $a registrace $7 D012042
- 650 _2
- $a retrospektivní studie $7 D012189
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 655 _2
- $a komentáře $7 D016420
- 700 1_
- $a Habib, Gilbert $u Department of Cardiology, Hôpital de la Timone, Aix-Marseille University, Marseille University Hospital, Marseille, France $u Aix Marseille University, IRD, AP-HM, MEPHI, IHU-Mediterranean Infection, Marseille, France $1 https://orcid.org/0000000338999983
- 700 1_
- $a Laroche, Cécile $u EURObservational Research Programme, European Society of Cardiology, Heart House, Sophia Antipolis, France
- 700 1_
- $a Stöhr, Elisabeth $u Department of Cardiology, Heart Center, University of Bonn, Bonn, Germany
- 700 1_
- $a Chirouze, Catherine $u Maladies Infectieuses et Tropicales - Centre Hospitalier Régional Universitaire, Besançon, France; UMR-CNRS 6249 Chrono-Environnement, Université Bourgogne Franche-Comté, Besançon, France
- 700 1_
- $a Hernandez-Meneses, Marta $u Department of Infectious Diseases, Hospital Clinic of Barcelona-IDIBAPS, University of Barcelona, Barcelona, Spain
- 700 1_
- $a Melissopoulou, Maria $u Department of Cardiology, CHR Citadelle, Liège, Belgium
- 700 1_
- $a Mutlu, Bülent $u Department of Cardiology, Marmara University Istanbul Pendik Educational and Research Hospital, Istanbul, Turkey
- 700 1_
- $a Scheggi, Valentina $u Division of Cardiovascular and Perioperative Medicine, Cardiothoracovascular Department, Azienda Ospedaliero-Universitaria Careggi and University of Florence, Florence, Italy
- 700 1_
- $a Branco, Luísa $u Department of Cardiology, Santa Marta Hospital, Lisbon, Portugal
- 700 1_
- $a Olmos, Carmen $u Instituto Cardiovascular, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdSSC), Madrid, Spain
- 700 1_
- $a Reyes, Graciela $u Echo Lab Department, Hospital de Alta Complejidad en red El Cruce, Florencio Varela, Buenos Aires, Argentina
- 700 1_
- $a Pazdernik, Michal $u Department of Cardiology, IKEM, Prague, Czech Republic; Department of Cardiology, 2nd Medical School, Charles University, University Hospital Motol, Prague, Czech Republic
- 700 1_
- $a Iung, Bernard $u Université de Paris and Institut National de la Santé et de la Recherche Scientifique 1148, Paris, France $u Cardiology Department, Bichat Hospital AP-HP, Paris, France $1 https://orcid.org/000000029127348X
- 700 1_
- $a Sow, Rouguiatou $u Department of cardiology, Luxembourg Hospital Centre, Luxembourg, Luxembourg
- 700 1_
- $a Mirocevic, Maja $u Department of Cardiology, Clinical Centre of Montenegro, Podgorica, Montenegro
- 700 1_
- $a Lancellotti, Patrizio $u Cardiology Department, University Hospital Centre, Centre Hospitalier Universitaire (CHU) Sart Tilman, Liège, Belgium $1 https://orcid.org/0000000208048194
- 700 1_
- $a Tribouilloy, Christophe $u Department of Cardiology, Amiens University Hospital, Amiens, France $u UR UPJV 7517, Jules Verne University of Picardie, Amiens, France
- 710 2_
- $a EORP EURO-ENDO Registry Investigators Group
- 773 0_
- $w MED00006634 $t European journal of heart failure $x 1879-0844 $g Roč. 24, č. 7 (2022), s. 1253-1265
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/35508915 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20221017 $b ABA008
- 991 __
- $a 20221031100129 $b ABA008
- 999 __
- $a ok $b bmc $g 1854826 $s 1176600
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2022 $b 24 $c 7 $d 1253-1265 $e 20220516 $i 1879-0844 $m European journal of heart failure $n Eur J Heart Fail $x MED00006634
- LZP __
- $a Pubmed-20221017
