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Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model

G. Schalk, S. Worrell, F. Mivalt, A. Belsten, I. Kim, JM. Morris, D. Hermes, BT. Klassen, NP. Staff, S. Messina, T. Kaufmann, J. Rickert, P. Brunner, GA. Worrell, KJ. Miller

. 2022 ; 16 (-) : 932782. [pub] 20221219

Status not-indexed Language English Country Switzerland

Document type Journal Article

Grant support
KL2 TR002379 NCATS NIH HHS - United States
U24 NS109103 NINDS NIH HHS - United States
R01 MH122258 NIMH NIH HHS - United States
U01 NS128612 NINDS NIH HHS - United States
R01 EB026439 NIBIB NIH HHS - United States
UH3 NS095495 NINDS NIH HHS - United States
P41 EB018783 NIBIB NIH HHS - United States

This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.

References provided by Crossref.org

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