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Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model
G. Schalk, S. Worrell, F. Mivalt, A. Belsten, I. Kim, JM. Morris, D. Hermes, BT. Klassen, NP. Staff, S. Messina, T. Kaufmann, J. Rickert, P. Brunner, GA. Worrell, KJ. Miller
Status not-indexed Language English Country Switzerland
Document type Journal Article
Grant support
KL2 TR002379
NCATS NIH HHS - United States
U24 NS109103
NINDS NIH HHS - United States
R01 MH122258
NIMH NIH HHS - United States
U01 NS128612
NINDS NIH HHS - United States
R01 EB026439
NIBIB NIH HHS - United States
UH3 NS095495
NINDS NIH HHS - United States
P41 EB018783
NIBIB NIH HHS - United States
NLK
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- Publication type
- Journal Article MeSH
This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.
Chen Frontier Lab for Applied Neurotechnology Tianqiao and Chrissy Chen Institute Shanghai China
Department of Biomedical Engineering Brno University of Technology Brno Czechia
Department of Neurology Mayo Clinic Rochester MN United States
Department of Neuroradiology Mayo Clinic Rochester MN United States
Department of Neurosurgery Mayo Clinic Rochester MN United States
Department of Neurosurgery Washington University in St Louis St Louis MO United States
Department of Physiology and Biomedical Engineering Mayo Clinic Rochester MN United States
National Center for Adaptive Neurotechnologies Albany NY United States
References provided by Crossref.org
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