-
Je něco špatně v tomto záznamu ?
The Role of Exosomes in Human Carcinogenesis and Cancer Therapy-Recent Findings from Molecular and Clinical Research
K. Stefańska, M. Józkowiak, A. Angelova Volponi, JA. Shibli, A. Golkar-Narenji, P. Antosik, D. Bukowska, H. Piotrowska-Kempisty, P. Mozdziak, P. Dzięgiel, M. Podhorska-Okołów, M. Zabel, M. Dyszkiewicz-Konwińska, B. Kempisty
Jazyk angličtina Země Švýcarsko
Typ dokumentu časopisecké články, přehledy, Research Support, U.S. Gov't, Non-P.H.S.
NLK
Directory of Open Access Journals
od 2012
Free Medical Journals
od 2012
PubMed Central
od 2012
Europe PubMed Central
od 2012
ProQuest Central
od 2012-03-01
Open Access Digital Library
od 2012-01-01
Open Access Digital Library
od 2012-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2012
PubMed
36766698
DOI
10.3390/cells12030356
Knihovny.cz E-zdroje
- MeSH
- exozómy * fyziologie MeSH
- karcinogeneze MeSH
- lékové transportní systémy MeSH
- lidé MeSH
- nádory * patologie MeSH
- nosiče léků terapeutické užití MeSH
- savci MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Research Support, U.S. Gov't, Non-P.H.S. MeSH
Exosomes are biological nanoscale spherical lipid bilayer vesicles, 40-160 nm in diameter, produced by most mammalian cells in both physiological and pathological conditions. Exosomes are formed via the endosomal sorting complex required for transport (ESCRT). The primary function of exosomes is mediating cell-to-cell communication. In terms of cancer, exosomes play important roles as mediators of intercellular communication, leading to tumor progression. Moreover, they can serve as biomarkers for cancer detection and progression. Therefore, their utilization in cancer therapies has been suggested, either as drug delivery carriers or as a diagnostic tool. However, exosomes were also reported to be involved in cancer drug resistance via transferring information of drug resistance to sensitive cells. It is important to consider the current knowledge regarding the role of exosomes in cancer, drug resistance, cancer therapies, and their clinical application in cancer therapies.
Cellivia 3 S A 61 623 Poznan Poland
Department of Histology and Embryology Poznan University of Medical Sciences 60 781 Poznan Poland
Department of Toxicology Poznan University of Medical Sciences 60 631 Poznan Poland
Division of Anatomy and Histology University of Zielona Góra 65 046 Zielona Góra Poland
Prestage Department of Poultry Sciences North Carolina State University Raleigh NC 27695 USA
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc23004558
- 003
- CZ-PrNML
- 005
- 20230425171608.0
- 007
- ta
- 008
- 230418s2023 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/cells12030356 $2 doi
- 035 __
- $a (PubMed)36766698
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Stefańska, Katarzyna $u Department of Histology and Embryology, Poznan University of Medical Sciences, 60-781 Poznan, Poland $u Cellivia 3 S.A., 61-623 Poznan, Poland $1 https://orcid.org/0000000288144935
- 245 14
- $a The Role of Exosomes in Human Carcinogenesis and Cancer Therapy-Recent Findings from Molecular and Clinical Research / $c K. Stefańska, M. Józkowiak, A. Angelova Volponi, JA. Shibli, A. Golkar-Narenji, P. Antosik, D. Bukowska, H. Piotrowska-Kempisty, P. Mozdziak, P. Dzięgiel, M. Podhorska-Okołów, M. Zabel, M. Dyszkiewicz-Konwińska, B. Kempisty
- 520 9_
- $a Exosomes are biological nanoscale spherical lipid bilayer vesicles, 40-160 nm in diameter, produced by most mammalian cells in both physiological and pathological conditions. Exosomes are formed via the endosomal sorting complex required for transport (ESCRT). The primary function of exosomes is mediating cell-to-cell communication. In terms of cancer, exosomes play important roles as mediators of intercellular communication, leading to tumor progression. Moreover, they can serve as biomarkers for cancer detection and progression. Therefore, their utilization in cancer therapies has been suggested, either as drug delivery carriers or as a diagnostic tool. However, exosomes were also reported to be involved in cancer drug resistance via transferring information of drug resistance to sensitive cells. It is important to consider the current knowledge regarding the role of exosomes in cancer, drug resistance, cancer therapies, and their clinical application in cancer therapies.
- 650 _2
- $a zvířata $7 D000818
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a exozómy $x fyziologie $7 D055354
- 650 12
- $a nádory $x patologie $7 D009369
- 650 _2
- $a nosiče léků $x terapeutické užití $7 D004337
- 650 _2
- $a lékové transportní systémy $7 D016503
- 650 _2
- $a karcinogeneze $7 D063646
- 650 _2
- $a savci $7 D008322
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a přehledy $7 D016454
- 655 _2
- $a Research Support, U.S. Gov't, Non-P.H.S. $7 D013486
- 700 1_
- $a Józkowiak, Małgorzata $u Department of Toxicology, Poznan University of Medical Sciences, 60-631 Poznan, Poland
- 700 1_
- $a Angelova Volponi, Ana $u Centre for Craniofacial and Regenerative Biology, Dental Institute, King's College London, London WC2R 2LS, UK $1 https://orcid.org/0000000256610807
- 700 1_
- $a Shibli, Jamil Awad $u Department of Periodontology and Oral Implantology, University of Guarulhos, Guarulhos 07030-010, Brazil
- 700 1_
- $a Golkar-Narenji, Afsaneh $u Prestage Department of Poultry Sciences, North Carolina State University, Raleigh, NC 27695, USA
- 700 1_
- $a Antosik, Paweł $u Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland
- 700 1_
- $a Bukowska, Dorota $u Department of Diagnostics and Clinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland
- 700 1_
- $a Piotrowska-Kempisty, Hanna $u Department of Toxicology, Poznan University of Medical Sciences, 60-631 Poznan, Poland $u Department of Basic and Preclinical Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland
- 700 1_
- $a Mozdziak, Paul $u Prestage Department of Poultry Sciences, North Carolina State University, Raleigh, NC 27695, USA $1 https://orcid.org/0000000215753123
- 700 1_
- $a Dzięgiel, Piotr $u Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland $1 https://orcid.org/0000000282921385
- 700 1_
- $a Podhorska-Okołów, Marzenna $u Division of Ultrastructural Research, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland
- 700 1_
- $a Zabel, Maciej $u Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland $u Division of Anatomy and Histology, University of Zielona Góra, 65-046 Zielona Góra, Poland
- 700 1_
- $a Dyszkiewicz-Konwińska, Marta $u Department of Biomaterials and Experimental Dentistry, Poznan University of Medical Sciences, 60-812 Poznan, Poland $1 https://orcid.org/0000000280699004
- 700 1_
- $a Kempisty, Bartosz $u Prestage Department of Poultry Sciences, North Carolina State University, Raleigh, NC 27695, USA $u Department of Veterinary Surgery, Institute of Veterinary Medicine, Nicolaus Copernicus University in Torun, 87-100 Torun, Poland $u Division of Anatomy, Department of Human Morphology and Embryology, Wroclaw Medical University, 50-368 Wroclaw, Poland $u Department of Obstetrics and Gynecology, University Hospital and Masaryk University, 601 77 Brno, Czech Republic
- 773 0_
- $w MED00194911 $t Cells $x 2073-4409 $g Roč. 12, č. 3 (2023)
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/36766698 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20230418 $b ABA008
- 991 __
- $a 20230425171605 $b ABA008
- 999 __
- $a ok $b bmc $g 1924947 $s 1190767
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2023 $b 12 $c 3 $e 20230118 $i 2073-4409 $m Cells $n Cells $x MED00194911
- LZP __
- $a Pubmed-20230418
