-
Je něco špatně v tomto záznamu ?
Retrospective Analysis of Retroperitoneal-Abdominal-Pelvic Ganglioneuromas: An International Study by the Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)
S. Noh, C. Nessim, EZ. Keung, CL. Roland, D. Strauss, G. Sivarajah, M. Fiore, D. Biasoni, SPB. Cioffi, W. Mehtsun, FCM. Cananzi, F. Sicoli, V. Quagliuolo, J. Chen, C. Luo, RA. Gladdy, C. Swallow, W. Johnston, SJ. Ford, C. Evenden, F. Tirotta, M....
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, Research Support, N.I.H., Extramural, práce podpořená grantem
Grantová podpora
P30 CA008748
NCI NIH HHS - United States
P30 CA023100
NCI NIH HHS - United States
R01 CA226803
NCI NIH HHS - United States
- MeSH
- dospělí MeSH
- ganglioneurom * chirurgie MeSH
- lidé MeSH
- nádory měkkých tkání * MeSH
- neuroblastom * MeSH
- progrese nemoci MeSH
- retroperitoneální nádory * chirurgie MeSH
- retrospektivní studie MeSH
- sarkom * chirurgie patologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Research Support, N.I.H., Extramural MeSH
OBJECTIVE: The Transatlantic Australasian Retroperitoneal Sarcoma Working Group conducted a retrospective study on the disease course and clinical management of ganglioneuromas. BACKGROUND: Ganglioneuromas are rare tumors derived from neural crest cells. Data on these tumors remain limited to case reports and single-institution case series. METHODS: Patients of all ages with pathologically confirmed primary retroperitoneal, intra-abdominal, and pelvic ganglioneuromas between January 1, 2000, and January 1, 2020, were included. We examined demographic, clinicopathologic, and radiologic characteristics, as well as clinical management. RESULTS: Overall, 328 patients from 29 institutions were included. The median age at diagnosis was 37 years with 59.1% of patients being female. Symptomatic presentation comprised 40.9% of cases, and tumors were often located in the extra-adrenal retroperitoneum (67.1%). At baseline, the median maximum tumor diameter was 7.2 cm. One hundred sixteen (35.4%) patients underwent active surveillance, whereas 212 (64.6%) patients underwent resection with 74.5% of operative cases achieving an R0/R1 resection. Serial tumor evaluations showed that malignant transformation to neuroblastoma was rare (0.9%, N=3). Tumors undergoing surveillance had a median follow-up of 1.9 years, with 92.2% of ganglioneuromas stable in size. With a median follow-up of 3.0 years for resected tumors, 84.4% of patients were disease free after resections, whereas recurrences were observed in 4 (1.9%) patients. CONCLUSIONS: Most ganglioneuromas have indolent disease courses and rarely transform to neuroblastoma. Thus, active surveillance may be appropriate for benign and asymptomatic tumors particularly when the risks of surgery outweigh the benefits. For symptomatic or growing tumors, resection may be curative.
Center for Sarcoma and Bone Oncology Dana Farber Cancer Institute Boston MA
College of Osteopathic Medicine of the Pacific Western University of Health Sciences Pomona CA
Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy
Department of Cancer Surgery Peter MacCallum Cancer Centre Melbourne Victoria Australia
Department of Comprehensive Cancer Care Masaryk Memorial Cancer Institute Brno Czech Republic
Department of Medical Oncology Bern University Hospital University of Bern Bern Switzerland
Department of Medical Oncology Campus Bio Medico University of Rome Rome Italy
Department of Paediatric Oncology University Hospitals Leuven Belgium
Department of Retroperitoneal Tumor Surgery Peking University International Hospital Beijing China
Department of Surgery Brigham and Women's Hospital Boston MA
Department of Surgery Fondazione IRCCS Istituto Nazionale dei Tumori Milan Italy
Department of Surgery The Ottawa Hospital Ottawa Hospital Research Institute Ottawa ON Canada
Department of Surgery University of Washington Seattle WA
Department of Surgical Oncology Fox Chase Cancer Center Philadelphia PA
Department of Surgical Oncology Institut Curie PSL University Paris France
Department of Surgical Oncology Institute of Oncology Ljubljana Zaloška Ljubljana Slovenia
Department of Surgical Oncology Royal Marsden Hospital London UK
Department of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston TX
Department of Surgical Oncology University Hospitals Gasthuisberg Leuven Belgium
Division of Medical Oncology Sarcoma Unit Candiolo Cancer Institute FPO IRCCS Candiolo Italy
Division of Melanoma Sarcoma and Rare Tumors IRCCS European Institute of Oncology Milan Italy
Division of Musculoskeletal Oncology National Cancer Center Hospital Tokyo Japan
Harvard Medical School Boston MA
Sarcoma Melanoma and Rare Tumors Surgery Unit IRCCS Humanitas Research Hospital Rozzano Milan Italy
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc23016793
- 003
- CZ-PrNML
- 005
- 20240206090449.0
- 007
- ta
- 008
- 231013s2023 xxu f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1097/SLA.0000000000005625 $2 doi
- 035 __
- $a (PubMed)35866666
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Noh, Sangkyu $u Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California San Diego, UC San Diego Health Sciences, La Jolla, CA $u College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA
- 245 10
- $a Retrospective Analysis of Retroperitoneal-Abdominal-Pelvic Ganglioneuromas: An International Study by the Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) / $c S. Noh, C. Nessim, EZ. Keung, CL. Roland, D. Strauss, G. Sivarajah, M. Fiore, D. Biasoni, SPB. Cioffi, W. Mehtsun, FCM. Cananzi, F. Sicoli, V. Quagliuolo, J. Chen, C. Luo, RA. Gladdy, C. Swallow, W. Johnston, SJ. Ford, C. Evenden, F. Tirotta, M. Almond, L. Nguyen, P. Rutkowski, M. Krotewicz, E. Pennacchioli, K. Cardona, A. Gamboa, D. Hompes, M. Renard, A. Kollár, CO. Ryser, N. Vassos, CP. Raut, M. Fairweather, DA. Krakorova, S. Quildrian, A. Perhavec, E. Nizri, JM. Farma, SH. Greco, B. Vincenzi, JAG. Lopez, MS. Solerdecoll, S. Iwata, S. Fukushima, T. Kim, F. Tolomeo, H. Snow, Y. Howlett-Jansen, D. Tzanis, M. Nikulin, A. Gronchi, JK. Sicklick, Transatlantic Australasian Retroperitoneal Sarcoma Working Group
- 520 9_
- $a OBJECTIVE: The Transatlantic Australasian Retroperitoneal Sarcoma Working Group conducted a retrospective study on the disease course and clinical management of ganglioneuromas. BACKGROUND: Ganglioneuromas are rare tumors derived from neural crest cells. Data on these tumors remain limited to case reports and single-institution case series. METHODS: Patients of all ages with pathologically confirmed primary retroperitoneal, intra-abdominal, and pelvic ganglioneuromas between January 1, 2000, and January 1, 2020, were included. We examined demographic, clinicopathologic, and radiologic characteristics, as well as clinical management. RESULTS: Overall, 328 patients from 29 institutions were included. The median age at diagnosis was 37 years with 59.1% of patients being female. Symptomatic presentation comprised 40.9% of cases, and tumors were often located in the extra-adrenal retroperitoneum (67.1%). At baseline, the median maximum tumor diameter was 7.2 cm. One hundred sixteen (35.4%) patients underwent active surveillance, whereas 212 (64.6%) patients underwent resection with 74.5% of operative cases achieving an R0/R1 resection. Serial tumor evaluations showed that malignant transformation to neuroblastoma was rare (0.9%, N=3). Tumors undergoing surveillance had a median follow-up of 1.9 years, with 92.2% of ganglioneuromas stable in size. With a median follow-up of 3.0 years for resected tumors, 84.4% of patients were disease free after resections, whereas recurrences were observed in 4 (1.9%) patients. CONCLUSIONS: Most ganglioneuromas have indolent disease courses and rarely transform to neuroblastoma. Thus, active surveillance may be appropriate for benign and asymptomatic tumors particularly when the risks of surgery outweigh the benefits. For symptomatic or growing tumors, resection may be curative.
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 12
- $a ganglioneurom $x chirurgie $7 D005729
- 650 12
- $a retroperitoneální nádory $x chirurgie $7 D012186
- 650 12
- $a sarkom $x chirurgie $x patologie $7 D012509
- 650 12
- $a nádory měkkých tkání $7 D012983
- 650 _2
- $a progrese nemoci $7 D018450
- 650 12
- $a neuroblastom $7 D009447
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a Research Support, N.I.H., Extramural $7 D052061
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Nessim, Carolyn $u Department of Surgery, The Ottawa Hospital, Ottawa Hospital Research Institute, Ottawa, ON, Canada
- 700 1_
- $a Keung, Emily Z $u Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
- 700 1_
- $a Roland, Christina L $u Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
- 700 1_
- $a Strauss, Dirk $u Department of Surgical Oncology, Royal Marsden Hospital, London, UK
- 700 1_
- $a Sivarajah, Gausihi $u Department of Surgical Oncology, Royal Marsden Hospital, London, UK
- 700 1_
- $a Fiore, Marco $u Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
- 700 1_
- $a Biasoni, Davide $u Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
- 700 1_
- $a Cioffi, Stefano Piero Bernardo $u Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
- 700 1_
- $a Mehtsun, Winta $u Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California San Diego, UC San Diego Health Sciences, La Jolla, CA
- 700 1_
- $a Cananzi, Ferdinando Carlo Maria $u Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy $u Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
- 700 1_
- $a Sicoli, Federico $u Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy $u Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
- 700 1_
- $a Quagliuolo, Vittorio $u Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy $u Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
- 700 1_
- $a Chen, Jun $u Department of Retroperitoneal Tumor Surgery, Peking University International Hospital, Beijing, China
- 700 1_
- $a Luo, Chenghua $u Department of Retroperitoneal Tumor Surgery, Peking University International Hospital, Beijing, China
- 700 1_
- $a Gladdy, Rebecca A $u Department of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, Toronto, ON, Canada
- 700 1_
- $a Swallow, Carol $u Department of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, Toronto, ON, Canada
- 700 1_
- $a Johnston, Wendy $u Department of Surgical Oncology, Mount Sinai Hospital and Princess Margaret Cancer Centre, Toronto, ON, Canada
- 700 1_
- $a Ford, Samuel J $u Midlands Abdominal and Retroperitoneal Sarcoma Unit (MARSU), University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
- 700 1_
- $a Evenden, Caroline $u Midlands Abdominal and Retroperitoneal Sarcoma Unit (MARSU), University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
- 700 1_
- $a Tirotta, Fabio $u Midlands Abdominal and Retroperitoneal Sarcoma Unit (MARSU), University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
- 700 1_
- $a Almond, Max $u Midlands Abdominal and Retroperitoneal Sarcoma Unit (MARSU), University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
- 700 1_
- $a Nguyen, Laura $u Department of Surgery, The Ottawa Hospital, Ottawa Hospital Research Institute, Ottawa, ON, Canada
- 700 1_
- $a Rutkowski, Piotr $u Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
- 700 1_
- $a Krotewicz, Maria $u Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
- 700 1_
- $a Pennacchioli, Elisabetta $u Division of Melanoma, Sarcoma and Rare Tumors, IRCCS, European Institute of Oncology, Milan, Italy
- 700 1_
- $a Cardona, Kenneth $u Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA
- 700 1_
- $a Gamboa, Adriana $u Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA
- 700 1_
- $a Hompes, Daphne $u Department of Surgical Oncology, University Hospitals Gasthuisberg, Leuven, Belgium
- 700 1_
- $a Renard, Marleen $u Department of Paediatric Oncology, University Hospitals, Leuven, Belgium
- 700 1_
- $a Kollár, Attila $u Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland
- 700 1_
- $a Ryser, Christoph O $u Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland
- 700 1_
- $a Vassos, Nikolaos $u Division of Surgical Oncology, Department of Surgery, Mannheim University Medical Centre, University of Heidelberg, Mannheim, Germany
- 700 1_
- $a Raut, Chandrajit P $u Department of Surgery, Brigham and Women's Hospital, Boston, MA $u Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, MA $u Harvard Medical School, Boston, MA
- 700 1_
- $a Fairweather, Mark $u Department of Surgery, Brigham and Women's Hospital, Boston, MA $u Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Boston, MA $u Harvard Medical School, Boston, MA
- 700 1_
- $a Adámková Krákorová, Dagmar $u Department of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Brno, Czech Republic $7 xx0084127
- 700 1_
- $a Quildrian, Sergio $u Sarcoma and Melanoma Unit, General Surgery Department, Buenos Aires British Hospital, Buenos Aires, Argentina $u Sarcoma and Melanoma Unit, Angel H Roffo Institute of Oncology, University of Buenos Aires, Buenos Aires, Argentina $1 https://orcid.org/0000000157947084
- 700 1_
- $a Perhavec, Andraz $u Department of Surgical Oncology, Institute of Oncology Ljubljana, Zaloška, Ljubljana, Slovenia
- 700 1_
- $a Nizri, Eran $u Surgical Oncology Unit, Department of Surgery, The Sackler Faculty of Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Tel-Aviv, Israel
- 700 1_
- $a Farma, Jeffrey M $u Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA
- 700 1_
- $a Greco, Stephanie H $u Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA
- 700 1_
- $a Vincenzi, Bruno $u Department of Medical Oncology, Campus Bio-Medico University of Rome, Rome, Italy
- 700 1_
- $a Lopez, José Antonio González $u Unidad de Mama y Pared Abdominal, Servicio de Cirugía General y Digestiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España
- 700 1_
- $a Solerdecoll, Mireia Solans $u Unidad de Mama y Pared Abdominal, Servicio de Cirugía General y Digestiva, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España
- 700 1_
- $a Iwata, Shintaro $u Division of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan
- 700 1_
- $a Fukushima, Suguru $u Division of Musculoskeletal Oncology, National Cancer Center Hospital, Tokyo, Japan
- 700 1_
- $a Kim, Teresa $u Department of Surgery, University of Washington, Seattle, WA
- 700 1_
- $a Tolomeo, Francesco $u Division of Medical Oncology, Sarcoma Unit, Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Italy
- 700 1_
- $a Snow, Hayden $u Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
- 700 1_
- $a Howlett-Jansen, Ynez $u Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
- 700 1_
- $a Tzanis, Dimitri $u Division of Medical Oncology, Sarcoma Unit, Candiolo Cancer Institute-FPO, IRCCS, Candiolo, Italy $u Department of Surgical Oncology, Institut Curie, PSL University, Paris, France
- 700 1_
- $a Nikulin, Maxim $u Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia $u N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of Russia, Moscow, Russia
- 700 1_
- $a Gronchi, Alessandro $u Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
- 700 1_
- $a Sicklick, Jason K $u Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California San Diego, UC San Diego Health Sciences, La Jolla, CA
- 710 2_
- $a Transatlantic Australasian Retroperitoneal Sarcoma Working Group
- 773 0_
- $w MED00009202 $t Annals of surgery $x 1528-1140 $g Roč. 278, č. 2 (2023), s. 267-273
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/35866666 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20231013 $b ABA008
- 991 __
- $a 20240206090446 $b ABA008
- 999 __
- $a ok $b bmc $g 2000373 $s 1203155
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2023 $b 278 $c 2 $d 267-273 $e 20220722 $i 1528-1140 $m Annals of surgery $n Ann Surg $x MED00009202
- GRA __
- $a P30 CA008748 $p NCI NIH HHS $2 United States
- GRA __
- $a P30 CA023100 $p NCI NIH HHS $2 United States
- GRA __
- $a R01 CA226803 $p NCI NIH HHS $2 United States
- LZP __
- $a Pubmed-20231013
