Detail
Článek
Článek online
FT
Medvik - BMČ
  • Je něco špatně v tomto záznamu ?

The Cytological Energy Detection of Purulent Inflammation in Synovial Fluid Is Not All Black and White

P. Kelbich, E. Vanaskova, K. Hrach, J. Krejsek, F. Smisko, P. Hruskova, E. Hanuljakova, T. Novotny

. 2024 ; 12 (3) : . [pub] 20240316

Status neindexováno Jazyk angličtina Země Švýcarsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24005570

Grantová podpora
IGA-KZ-2021-1-1 The Internal Grant of the Krajská zdravotní, a.s. in Usti nad Labem, Czech Republic
Cooperatio Program, research area IMMU Charles University in Prague, Faculty of Medicine in Hradec Kralove, Czech Republic

Neutrophils are frequently found in the cytological picture of synovial fluid in several joint pathologies, and a higher proportion of them can even wrongly indicate these cases as purulent inflammation. For reliable differentiation between purulent and non-purulent cases, we use the cytological energy analysis of the synovial fluid. Using this method, we examined 350 knee joint synovial fluid samples. Overall, we found that the percentage of neutrophils ranged between 20.0% and 50.0% in 44 (12.6%) cases and was above 50.0% in 231 (66.0%) cases. In the same group, only 85 (24.3%) highly anaerobic synovial fluid samples were evaluated as purulent inflammation, and another 17 (4.9%) cases were evaluated as very likely purulent inflammation. Further, we quantified the immediate risk of purulent inflammation using the "purulent score" (PS). Of the total of 350 samples, 103 (29.4%) cases were classified as having a very high risk of purulent inflammation (PS = 4), 53 (15.1%) cases were classified as having a significant risk of purulent inflammation (PS = 3), 17 (4.9%) cases were classified as having a moderate risk of purulent inflammation (PS = 2), and 75 (21.4%) cases were classified as having no immediate risk of purulent inflammation (PS = 1). Based on our results and analyses, the cytological energy analysis of synovial fluid is an effective method that can be used to detect and specify joint inflammation and the risk of septic arthritis development.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc24005570
003      
CZ-PrNML
005      
20250610090243.0
007      
ta
008      
240405s2024 sz f 000 0|eng||
009      
AR
024    7_
$a 10.3390/biomedicines12030667 $2 doi
035    __
$a (PubMed)38540280
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a sz
100    1_
$a Kelbich, Petr $u Department of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic $u Department of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic $u Laboratory for Cerebrospinal Fluid, Neuroimmunology, Pathology and Special Diagnostics Topelex, 190 00 Prague, Czech Republic $1 https://orcid.org/0000000292616827
245    14
$a The Cytological Energy Detection of Purulent Inflammation in Synovial Fluid Is Not All Black and White / $c P. Kelbich, E. Vanaskova, K. Hrach, J. Krejsek, F. Smisko, P. Hruskova, E. Hanuljakova, T. Novotny
520    9_
$a Neutrophils are frequently found in the cytological picture of synovial fluid in several joint pathologies, and a higher proportion of them can even wrongly indicate these cases as purulent inflammation. For reliable differentiation between purulent and non-purulent cases, we use the cytological energy analysis of the synovial fluid. Using this method, we examined 350 knee joint synovial fluid samples. Overall, we found that the percentage of neutrophils ranged between 20.0% and 50.0% in 44 (12.6%) cases and was above 50.0% in 231 (66.0%) cases. In the same group, only 85 (24.3%) highly anaerobic synovial fluid samples were evaluated as purulent inflammation, and another 17 (4.9%) cases were evaluated as very likely purulent inflammation. Further, we quantified the immediate risk of purulent inflammation using the "purulent score" (PS). Of the total of 350 samples, 103 (29.4%) cases were classified as having a very high risk of purulent inflammation (PS = 4), 53 (15.1%) cases were classified as having a significant risk of purulent inflammation (PS = 3), 17 (4.9%) cases were classified as having a moderate risk of purulent inflammation (PS = 2), and 75 (21.4%) cases were classified as having no immediate risk of purulent inflammation (PS = 1). Based on our results and analyses, the cytological energy analysis of synovial fluid is an effective method that can be used to detect and specify joint inflammation and the risk of septic arthritis development.
590    __
$a NEINDEXOVÁNO
655    _2
$a časopisecké články $7 D016428
700    1_
$a Vanaskova, Eliska $u Department of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic $u Department of Orthopaedics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic $1 https://orcid.org/0000000192112226
700    1_
$a Hrach, Karel $u Department of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic $u Faculty of Health Studies, Jan Evangelista Purkinje University, 400 96 Usti nad Labem, Czech Republic $1 https://orcid.org/000000027012053X $7 jo2003190654
700    1_
$a Krejsek, Jan $u Department of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic
700    1_
$a Smisko, Frantisek $u Department of Orthopaedics, Regional Hospital, 360 01 Karlovy Vary, Czech Republic
700    1_
$a Hruskova, Pavla $u Department of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic $u Department of Central Laboratories, Hospital Teplice, 415 29 Teplice, Czech Republic
700    1_
$a Hanuljakova, Eva $u Department of Biomedicine and Laboratory Diagnostics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic $u Laboratory for Cerebrospinal Fluid, Neuroimmunology, Pathology and Special Diagnostics Topelex, 190 00 Prague, Czech Republic
700    1_
$a Novotný, Tomáš $u Department of Orthopaedics, Faculty of Health Studies, Jan Evangelista Purkinje University and Masaryk Hospital, 401 13 Usti nad Labem, Czech Republic $u Department of Orthopaedic Surgery, Faculty of Medicine and University Hospital, Charles University in Prague, 500 03 Hradec Kralove, Czech Republic $1 https://orcid.org/0000000238550038 $7 xx0264903
773    0_
$w MED00205373 $t Biomedicines $x 2227-9059 $g Roč. 12, č. 3 (2024)
856    41
$u https://pubmed.ncbi.nlm.nih.gov/38540280 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y - $z 0
990    __
$a 20240405 $b ABA008
991    __
$a 20250610090236 $b ABA008
999    __
$a ok $b bmc $g 2075954 $s 1215332
BAS    __
$a 3
BAS    __
$a PreBMC-PubMed-not-MEDLINE
BMC    __
$a 2024 $b 12 $c 3 $e 20240316 $i 2227-9059 $m Biomedicines $n Biomedicines $x MED00205373
GRA    __
$a IGA-KZ-2021-1-1 $p The Internal Grant of the Krajská zdravotní, a.s. in Usti nad Labem, Czech Republic
GRA    __
$a Cooperatio Program, research area IMMU $p Charles University in Prague, Faculty of Medicine in Hradec Kralove, Czech Republic
LZP    __
$a Pubmed-20240405

Najít záznam

Citační ukazatele

Možnosti archivace