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Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist's geriatric assessment

I. Bužančić, M. Držaić, I. Kummer, M. Ortner Hadžiabdić, J. Brkić, D. Fialová

. 2024 ; 14 (1) : 6235. [pub] 20240314

Jazyk angličtina Země Anglie, Velká Británie

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24006729

Grantová podpora
MSCF-ITN-764632 Marie Skłodowska-Curie Foundation
No CZ.02.1.01/0.0/0.0/18_069/0010046 InoMed
No 965341, START / MED / 093 EN.02.2.69 / 0.0 / 0.0 / 19_073 / 0016935, SVV 260 551 European Horizon 2020 I-CARE4OLD
Research Unit: "Ageing, Polypharmacotherapy and Changes in Therapeutic Value of Drugs in the Aged'', KSKF-I. Cooperatio research program of the Faculty of Pharmacy, Charles University
CZ.02.01.01/00/22_008/0004607 NETPHARM project

Pharmacist's geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains. Data collected from a geriatric assessment questionnaire, for 388 patients, from the Croatian cohort of the EuroAgeism H2020 ESR 7 international project, along with guideline-based deprescribing criteria, were used to analyse potentially inappropriate prescribing of four medication groups (benzodiazepines (BZN), proton pump inhibitors (PPI), opioids, and non-steroidal anti-inflammatory drugs (NSAID)), and to assess the deprescribing potential. Binary logistic regression was used to explore the effects of age, gender, number of medicines and diagnoses, self-reported health, frailty score, and healthcare utilization on the likelihood of needing deprescribing. More than half of participants (n = 216, 55.2%) are candidates for deprescribing, with 31.1% of PPI, 74.8% of NSAID, 75% of opioid, and 96.1% of BZN users meeting at least one criterion. Most common criteria for deprescribing were inappropriately long use and safety concerns. Women (aOR = 2.58; p < 0.001), those reporting poor self-reported health (aOR = 5.14; p < 0.001), and those exposed to polypharmacy (aOR = 1.29; p < 0.001) had higher odds of needing to have medicines deprescribed. The high rate of deprescribing potential warrants prompt action to increase patient safety and decrease polypharmacy. Pharmacist's geriatric assessment and deprescribing-focused medication review could be used to lead a personalised approach.

Citace poskytuje Crossref.org

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