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Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980-2017

ML. Feldkamp, MA. Canfield, S. Krikov, D. Prieto-Merino, A. Šípek, N. LeLong, E. Amar, A. Rissmann, M. Csaky-Szunyogh, G. Tagliabue, A. Pierini, M. Gatt, JEH. Bergman, E. Szabova, E. Bermejo-Sánchez, D. Tucker, S. Dastgiri, MP. Bidondo, A....

. 2024 ; 116 (2) : e2306. [pub] -

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc24007223

BACKGROUND: Gastroschisis is a serious birth defect with midgut prolapse into the amniotic cavity. The objectives of this study were to evaluate the prevalence and time trends of gastroschisis among programs in the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR), focusing on regional variations and maternal age changes in the population. METHODS: We analyzed data on births from 1980 to 2017 from 27 ICBDSR member programs, representing 24 countries and three regions (Europe+ (includes Iran) , Latin America, North America). Cases were identified using diagnostic codes (i.e., 756.7, 756.71, or Q79.3). We excluded cases of amniotic band syndrome, limb-body wall defect, and ruptured omphalocele. Programs provided annual counts for gastroschisis cases (live births, stillbirths, and legally permitted pregnancy terminations for fetal anomalies) and source population (live births, stillbirths), by maternal age. RESULTS: Overall, gastroschisis occurred in 1 of every 3268 births (3.06 per 10,000 births; 95% confidence intervals [CI]: 3.01, 3.11), with marked regional variation. European+ prevalence was 1.49 (95%CI: 1.44, 1.55), Latin American 3.80 (95%CI: 3.69, 3.92) and North American 4.32 (95%CI: 4.22, 4.42). A statistically significant increasing time trend was observed among six European+ , four Latin American, and four North American programs. Women <20 years of age had the highest prevalence in all programs except the Slovak Republic. CONCLUSIONS: Gastroschisis prevalence increased over time in 61% of participating programs, and the highest increase in prevalence was observed among the youngest women. Additional inquiry will help to assess the impact of the changing maternal age proportions in the birth population on gastroschisis prevalence.

Birth Defects Epidemiology and Surveillance Branch Texas Department of State Health Services Austin Texas USA

Canadian Congenital Anomalies Surveillance System Centre for Surveillance and Applied Research Public Health Agency of Canada Ottawa Ontario Canada

Congenital Anomaly Register and Information Service for Wales Public Health Wales Knowledge Directorate Singleton Hospital Sketty Lane Swansea UK

Costa Rican Birth Defects Register Center Cartago Costa Rica

Czech Republic Department of Medical Genetics Thomayer Hospital Prague Czech Republic

Department of Epidemiology Fay W Boozman College of Public Health University of Arkansas for Medical Sciences and Arkansas Reproductive Health Monitoring System Arkansas Children's Research Institute Little Rock Arkansas USA

Department of Genetics Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán RYVEMCE Registry and Epidemiological Surveillance of Congenital Malformations Mexico City Mexico

Department of Genetics University of Groningen University Medical Center Groningen Groningen the Netherlands

Department of Medical Genetics and Pediatrics Alberta Congenital Anomalies Surveillance System Alberta Children's Hospital Calgary Alberta Canada

Department of Pediatrics The University of Utah Salt Lake City Utah USA

Division of Medical Genetics Department of Pediatrics University of Utah School of Medicine Salt Lake City Utah USA

ECEMC Instituto de Salud Carlos 3 Madrid Spain

ECLAMC Center for Medical Education and Clinical Research Buenos Aires Argentina

Facultad de Ciencias de la Salud Pontificia Universidad Javeriana Cali Cali Colombia

Faculty of Medicine Universidad de Alcalá Madrid Spain

Faculty of Public Health Slovak Medical University in Bratislava Bratislava Slovak Republic

France REMERA Registre des malformations en Rhône Alpes Hospices Civils de Lyon Lyon France

Health Services Management Research Centre Tabriz University of Medical Sciences Tabriz Iran

Hungarian Congenital Anomalies Registry and Rare Diseases Centre National Center for Public Health and Pharmacy Budapest Hungary

Instituto de Genética Humana Pontificia Universidad Javeriana Bogotá Bogotá Colombia

International Center on Birth Defects International Clearinghouse for Birth Defects Surveillance and Research Rome Italy

Lombardy Congenital Anomalies Registry Cancer Registry Unit Fondazione IRCCS Istituto Nazionale dei tumori Milan Italy

Malformation Monitoring Centre Saxony Anhalt Medical Faculty Otto von Guericke University Magdeburg Magdeburg Germany

Malta Congenital Anomalies Registry Directorate for Health Information and Research Pieta Malta

Metropolitan Atlanta Congenital Defects Program National Center on Birth Defects and Developmental Disabilities Centers for Disease Control and Prevention Atlanta Georgia USA

Mexico ReDeCo Monterrey Nuevo Leon Mexico

National Network of Congenital Anomalies of Argentina National Administration of Laboratories and Health Institutes National Ministry of Health Institutes Buenos Aires Argentina

Regional Register Congenital Malformation Maule Health Service Maule Chile

Unit of Epidemiology of Rare Diseases and Congenital Anomalies Institute of Clinical Physiology National Research Council and Fondazione Toscana Gabriele Monasterio Tuscany Registry of Congenital Defects Pisa Italy

Université Paris Cité Centre of Research in Epidemiology and StatisticS INSERM INRA Paris France

Utah Birth Defect Network Office of Children with Special Care Needs Division of Family Health Utah Department of Health and Human Services Salt Lake City Utah USA

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$a BACKGROUND: Gastroschisis is a serious birth defect with midgut prolapse into the amniotic cavity. The objectives of this study were to evaluate the prevalence and time trends of gastroschisis among programs in the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR), focusing on regional variations and maternal age changes in the population. METHODS: We analyzed data on births from 1980 to 2017 from 27 ICBDSR member programs, representing 24 countries and three regions (Europe+ (includes Iran) , Latin America, North America). Cases were identified using diagnostic codes (i.e., 756.7, 756.71, or Q79.3). We excluded cases of amniotic band syndrome, limb-body wall defect, and ruptured omphalocele. Programs provided annual counts for gastroschisis cases (live births, stillbirths, and legally permitted pregnancy terminations for fetal anomalies) and source population (live births, stillbirths), by maternal age. RESULTS: Overall, gastroschisis occurred in 1 of every 3268 births (3.06 per 10,000 births; 95% confidence intervals [CI]: 3.01, 3.11), with marked regional variation. European+ prevalence was 1.49 (95%CI: 1.44, 1.55), Latin American 3.80 (95%CI: 3.69, 3.92) and North American 4.32 (95%CI: 4.22, 4.42). A statistically significant increasing time trend was observed among six European+ , four Latin American, and four North American programs. Women <20 years of age had the highest prevalence in all programs except the Slovak Republic. CONCLUSIONS: Gastroschisis prevalence increased over time in 61% of participating programs, and the highest increase in prevalence was observed among the youngest women. Additional inquiry will help to assess the impact of the changing maternal age proportions in the birth population on gastroschisis prevalence.
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