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Patterns of aortic valve replacement in Europe and adoption by sex

S. Bleiziffer, C. Appleby, V. Delgado, H. Eltchaninoff, C. Gebhard, C. Hengstenberg, W. Wojakowski, N. Petersen, J. Kurucova, P. Bramlage, TK. Rudolph

. 2024 ; 406 (-) : 131996. [pub] 20240328

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články, multicentrická studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc24013402

OBJECTIVE: Management of patients with severe aortic stenosis (AS) may differ according to the patient sex. This study aimed to describe patterns of aortic valve replacement (AVR) for severe AS across Europe, including stratification by sex. METHODS: Procedure volume data for surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) for six years (2015-2020) were extracted from national databases for Austria, Czech Republic, Denmark, England, Finland, France, Germany, Norway, Poland, Spain, Sweden, and Switzerland and stratified by sex. Patients per million population (PPM) undergoing AVR per year were calculated using population estimates from Eurostat. RESULTS: Between 2015 and 2019, AVR procedures grew at an average annual rate of 3.9%. In 2020, the average total PPM undergoing AVR across all countries was 339, with 51% of procedures being TAVI and 49% SAVR. AVR PPM varied widely between countries, with the highest and lowest in Germany and Poland, respectively. The average total PPM was higher for men than women (423 vs. 258), but a higher proportion of women (62%) than men (44%) received TAVI. The proportion of TAVI among total AVR procedures increased with age, with an overall average of 96% of men and 98% of women aged ≥85 years receiving TAVI; however, adoption of TAVI varied by country. CONCLUSIONS: The analysis of temporal trends in the adoption of TAVI vs. SAVR across Europe showed significant variations. Despite the higher use of TAVI vs. SAVR in women, overall rates of AV intervention in women were lower compared to men.

Citace poskytuje Crossref.org

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$a Bleiziffer, Sabine $u Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre, North Rhine-Westphalia, University Hospital, Ruhr-University Bochum, Bad Oeynhausen, Germany. Electronic address: sbleiziffer@hdz-nrw.de
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$a Patterns of aortic valve replacement in Europe and adoption by sex / $c S. Bleiziffer, C. Appleby, V. Delgado, H. Eltchaninoff, C. Gebhard, C. Hengstenberg, W. Wojakowski, N. Petersen, J. Kurucova, P. Bramlage, TK. Rudolph
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$a OBJECTIVE: Management of patients with severe aortic stenosis (AS) may differ according to the patient sex. This study aimed to describe patterns of aortic valve replacement (AVR) for severe AS across Europe, including stratification by sex. METHODS: Procedure volume data for surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) for six years (2015-2020) were extracted from national databases for Austria, Czech Republic, Denmark, England, Finland, France, Germany, Norway, Poland, Spain, Sweden, and Switzerland and stratified by sex. Patients per million population (PPM) undergoing AVR per year were calculated using population estimates from Eurostat. RESULTS: Between 2015 and 2019, AVR procedures grew at an average annual rate of 3.9%. In 2020, the average total PPM undergoing AVR across all countries was 339, with 51% of procedures being TAVI and 49% SAVR. AVR PPM varied widely between countries, with the highest and lowest in Germany and Poland, respectively. The average total PPM was higher for men than women (423 vs. 258), but a higher proportion of women (62%) than men (44%) received TAVI. The proportion of TAVI among total AVR procedures increased with age, with an overall average of 96% of men and 98% of women aged ≥85 years receiving TAVI; however, adoption of TAVI varied by country. CONCLUSIONS: The analysis of temporal trends in the adoption of TAVI vs. SAVR across Europe showed significant variations. Despite the higher use of TAVI vs. SAVR in women, overall rates of AV intervention in women were lower compared to men.
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$a Appleby, Clare $u Department of Cardiology, Liverpool Heart and Chest Hospital, Thomas Dr, Liverpool L14 3PE, UK. Electronic address: clare.appleby@lhch.nhs.uk
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$a Delgado, Victoria $u Heart Institute, Department of Cardiology, Hospital University Germans Trias i Pujol Barcelona, Spain. Electronic address: videlga@gmail.com
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$a Eltchaninoff, Helene $u Department of Cardiology, Normandie Univ, UNIROUEN, U1096, CHU Rouen, F-76000 Rouen, France. Electronic address: helene.eltchaninoff@chu-rouen.fr
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$a Gebhard, Catherine $u Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 18, 3010 Bern, Switzerland. Electronic address: catherine.gebhard@insel.ch
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$a Hengstenberg, Christian $u Division of Cardiology, Department of Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: christian.hengstenberg@meduniwien.ac.at
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$a Wojakowski, Wojtek $u Division of Cardiology and Structural Heart Diseases, Medical University of Silesia, Ziolowa 45/47, Katowice 40-635, Poland. Electronic address: wojtek.wojakowski@gmail.com
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$a Petersen, Nathan $u Edwards Lifesciences, 1260 Nyon, Switzerland. Electronic address: nathan_petersen@edwards.com
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$a Kurucova, Jana $u Edwards Lifesciences, 18600 Prague, Czech Republic. Electronic address: jana_kurucova@edwards.com
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$a Bramlage, Peter $u Institute for Pharmacology and Preventive Medicine, Cloppenburg, Germany. Electronic address: peter.bramlage@ippmed.de
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$a Rudolph, Tanja K $u General and Interventional Cardiology/Angiology, Heart and Diabetes Centre, North Rhine-Westphalia, Bad Oeynhausen, Ruhr-University, Germany. Electronic address: trudolph@hdz-nrw.de
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