-
Je něco špatně v tomto záznamu ?
Treatment of thyroid disorder supported by 5-phosphodiesterase inhibitors improved erectile dysfunction in patients with hypo- and hyperthyroidism
M. Broul, P. Kučerová, E. Jozífková, K. Žižková
Jazyk angličtina Země Švédsko
Typ dokumentu časopisecké články
- MeSH
- dospělí MeSH
- erektilní dysfunkce * farmakoterapie MeSH
- hypertyreóza * komplikace farmakoterapie MeSH
- hypotyreóza * farmakoterapie komplikace MeSH
- inhibitory fosfodiesterasy 5 * terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
INTRODUCTION: The relationship between a poorly functioning thyroid gland and erectile dysfunction (hereinafter, "ED") has been demonstrated in many studies. If a man has thyroid problems, it can negatively affect his ability to achieve or maintain an erection. The thyroid gland produces hormones that affect metabolism and overall body function, including blood circulation. If the thyroid gland is not functioning properly, it can lead to blood circulation disorders, which can affect erectile function. There are also symptoms of thyroid disorders that can contribute to ED. Some of these symptoms include fatigue, depression, and anxiety, which can negatively affect a man's psychological side and affect his sexual performance. OBJECTIVES AND METHODS: In our article, we present a series of patients with ED who were treated in our department and found to have some form of thyroid dysfunction. RESULTS: After treatment for thyroid dysfunction and treatment with 5-phosphodiesterase inhibitors were implemented, erectile function improved in all patients ((Wilcoxon Signed Rank Test; Z = -4.55; p (2-tailed) < 0.001; n = 27) to the level of mild or no ED. Improvement occurred in men with hyper- and hypothyroidism. After one year of treatment, there was no difference between the two groups (t-test; t = 0.75; df = 0.25; p < 0.46). CONCLUSION: This study shows that screening for thyroid dysfunction should be performed in all men with ED and that treating thyroid dysfunction may be an effective way to improve erectile function in men with these health problems.
Department of Urology Krajská zdravotní a s Hospital Litoměřice o z Czech Republic
Gynecology Department Krajská zdravotní a s Chomutov Hospital o z Czech Republic
The Faculty of Health Studies J E Purkyně University in Ústí nad Labem Czech Republic
- 000
- 00000naa a2200000 a 4500
- 001
- bmc25004149
- 003
- CZ-PrNML
- 005
- 20250206105954.0
- 007
- ta
- 008
- 250121s2024 sw f 000 0|eng||
- 009
- AR
- 035 __
- $a (PubMed)39146564
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sw
- 100 1_
- $a Broul, Marek $u Department of Sexology, Krajská zdravotní, a.s., Masaryk Hospital in Ústí nad Labem, o.z., Sociální péče 3316/12a, Ústí nad Labem 40001, Czech Republic $u Department of Urology, Krajská zdravotní, a.s., Hospital Litoměřice, o.z., Czech Republic $u The Faculty of Health Studies, J. E. Purkyně University in Ústí nad Labem, Czech Republic
- 245 10
- $a Treatment of thyroid disorder supported by 5-phosphodiesterase inhibitors improved erectile dysfunction in patients with hypo- and hyperthyroidism / $c M. Broul, P. Kučerová, E. Jozífková, K. Žižková
- 520 9_
- $a INTRODUCTION: The relationship between a poorly functioning thyroid gland and erectile dysfunction (hereinafter, "ED") has been demonstrated in many studies. If a man has thyroid problems, it can negatively affect his ability to achieve or maintain an erection. The thyroid gland produces hormones that affect metabolism and overall body function, including blood circulation. If the thyroid gland is not functioning properly, it can lead to blood circulation disorders, which can affect erectile function. There are also symptoms of thyroid disorders that can contribute to ED. Some of these symptoms include fatigue, depression, and anxiety, which can negatively affect a man's psychological side and affect his sexual performance. OBJECTIVES AND METHODS: In our article, we present a series of patients with ED who were treated in our department and found to have some form of thyroid dysfunction. RESULTS: After treatment for thyroid dysfunction and treatment with 5-phosphodiesterase inhibitors were implemented, erectile function improved in all patients ((Wilcoxon Signed Rank Test; Z = -4.55; p (2-tailed) < 0.001; n = 27) to the level of mild or no ED. Improvement occurred in men with hyper- and hypothyroidism. After one year of treatment, there was no difference between the two groups (t-test; t = 0.75; df = 0.25; p < 0.46). CONCLUSION: This study shows that screening for thyroid dysfunction should be performed in all men with ED and that treating thyroid dysfunction may be an effective way to improve erectile function in men with these health problems.
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 12
- $a erektilní dysfunkce $x farmakoterapie $7 D007172
- 650 _2
- $a lidé středního věku $7 D008875
- 650 12
- $a inhibitory fosfodiesterasy 5 $x terapeutické užití $7 D058986
- 650 12
- $a hypertyreóza $x komplikace $x farmakoterapie $7 D006980
- 650 _2
- $a dospělí $7 D000328
- 650 12
- $a hypotyreóza $x farmakoterapie $x komplikace $7 D007037
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a výsledek terapie $7 D016896
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Kučerová, Petra $u Department of Sexology, Krajská zdravotní, a.s., Masaryk Hospital in Ústí nad Labem, o.z., Sociální péče 3316/12a, Ústí nad Labem 40001, Czech Republic $u Clinic of Urology and Robotic Surgery, Faculty of Health Studies, J.E. Purkyně University in Ústí nad Labem and Krajská zdravotní, a.s. - Masaryk Hospital in Ústí nad Labem, o.z., Czech Republic
- 700 1_
- $a Jozífková, Eva $u Department of Biology, Faculty of Science, Jan Evangelista Purkyně University, Ústí nad Labem, Czech Republic
- 700 1_
- $a Žižková, Kamila $u Department of Sexology, Krajská zdravotní, a.s., Masaryk Hospital in Ústí nad Labem, o.z., Sociální péče 3316/12a, Ústí nad Labem 40001, Czech Republic $u Gynecology Department, Krajská zdravotní, a.s., Chomutov Hospital, o.z., Czech Republic
- 773 0_
- $w MED00168352 $t Neuro-endocrinology letters $x 2354-4716 $g Roč. 45, č. 3 (2024), s. 180-187
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/39146564 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20250121 $b ABA008
- 991 __
- $a 20250206105950 $b ABA008
- 999 __
- $a ok $b bmc $g 2263727 $s 1240156
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2024 $b 45 $c 3 $d 180-187 $e 20240812 $i 2354-4716 $m Neuro-endocrinology letters $n Neuro Endocrinol Lett $x MED00168352
- LZP __
- $a Pubmed-20250121