A quantitative model of venous stasis thrombosis in rats
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
128018
Knihovny.cz E-resources
- MeSH
- Acute Disease MeSH
- Hemoglobins analysis MeSH
- Heparin therapeutic use MeSH
- Kaolin MeSH
- Rats MeSH
- Ligation MeSH
- Disease Models, Animal MeSH
- Thrombophlebitis blood drug therapy MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Hemoglobins MeSH
- Heparin MeSH
- Kaolin MeSH
A quantitative model of stasis-type of venous thrombosis in rats is described. The ligated bowel loop was used after provocation by an injection of kaolin. The mesenteric vessels of the loop were cut in a dish filled with distilled water and the extinction of escaped haemoglobin was measured photometrically. Heparin was highly effective in this model. Vessel wall lesion may be used or inducing thrombosis instead of kaolin.