The bactericidal activity of sera of healthy neonates and of newborns with hyperbilirubinaemia to Escherichia coli
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
378780
DOI
10.1007/bf02927298
Knihovny.cz E-zdroje
- MeSH
- baktericidní aktivita krve * MeSH
- dospělí MeSH
- Escherichia coli * MeSH
- fetální krev MeSH
- krevní transfuze MeSH
- lidé středního věku MeSH
- lidé MeSH
- novorozenec * MeSH
- novorozenecká žloutenka krev terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- novorozenec * MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Cord and newborn sera were found to possess a significantly decreased in vitro bactericidal activity to Escherichia coli as compared to sera of adult individuals. Hyperbilirubinaemia in neonates suffering from both Rh and ABO incompatibility results in a further significant impairment of the bactericidal activity of their sera in comparison with healthy newborn infants. Exchange transfusion improved considerably the serum bactericidal activity. The possible mechanism of toxic action of unconjugated bilirubin on cells of the immune system is discussed.
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