A study of occupational exposure to isopropylbiphenyls (Sure Sol-250)
Language English Country Netherlands Media print
Document type Journal Article
PubMed
2057762
DOI
10.1016/0048-9697(91)90112-r
PII: 0048-9697(91)90112-R
Knihovny.cz E-resources
- MeSH
- Acetylglucosaminidase urine MeSH
- Biphenyl Compounds analysis metabolism toxicity MeSH
- Adult MeSH
- Air Pollutants, Occupational analysis MeSH
- Humans MeSH
- Metabolic Clearance Rate MeSH
- Half-Life MeSH
- Occupational Exposure * MeSH
- Saliva chemistry MeSH
- Case-Control Studies MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Acetylglucosaminidase MeSH
- Biphenyl Compounds MeSH
- Air Pollutants, Occupational MeSH
- Sure-Sol 250 MeSH Browser
Environmental and medical examinations in workers exposed to the isopropylbiphenyl (IPBs) mixture, Sure Sol-250, in a capacitor-manufacturing plant were carried out once a year for three years. Levels of the total IPBs ranged from 0.03 to 36.6 mg/m3 with a mean of 5.6 mg/m3. The time-weighted average (TWA) exposures varied between 0.3 and 1.8 mg/m3. Physical and laboratory examinations (blood cell count, liver and kidney function tests and also antipyrine metabolism were normal) revealed no adverse effects of IPBs. Based on these observations as well as on the results of our six-month oral toxicity studies in rats, not presented in this paper, we recommend a TWA-MAC (maximum allowable concentration) of 10 mg/m3 for IPBs.
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