Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
2422063
Knihovny.cz E-resources
- MeSH
- Antigens, Surface analysis immunology MeSH
- beta 2-Microglobulin immunology MeSH
- Chromatography, Affinity MeSH
- Antigens, Differentiation, T-Lymphocyte MeSH
- Electrophoresis, Polyacrylamide Gel MeSH
- Enzyme-Linked Immunosorbent Assay MeSH
- Epitopes analysis MeSH
- Fluorescent Antibody Technique MeSH
- HLA-DR Antigens MeSH
- Hybridomas immunology MeSH
- Immunoglobulin kappa-Chains immunology MeSH
- Liver immunology MeSH
- Leukocytes classification immunology MeSH
- Humans MeSH
- Histocompatibility Antigens Class II immunology MeSH
- Monocytes immunology MeSH
- Antibodies, Monoclonal analysis biosynthesis MeSH
- Mice, Inbred BALB C immunology MeSH
- Mice MeSH
- T-Lymphocytes immunology MeSH
- Thymus Gland immunology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Antigens, Surface MeSH
- beta 2-Microglobulin MeSH
- Antigens, Differentiation, T-Lymphocyte MeSH
- Epitopes MeSH
- HLA-DR Antigens MeSH
- Immunoglobulin kappa-Chains MeSH
- Histocompatibility Antigens Class II MeSH
- Antibodies, Monoclonal MeSH
Monoclonal antibodies against several human leucocyte cell surface antigens were prepared and characterized: B2M-02, a non-cytotoxic antibody against beta-2-microglobulin; MEM-09 and MEM-40, against immunoglobulin kappa-type light chains; MEM-12, MEM-24G and MEM-32B, all against a monomorphic determinant in MHC class II antigens, presumably HLA-DR, dependent on the association of alpha and beta chains; MEM-15 and MEM-18, against a monocyte antigen of 55 kDa; MEM-28, against a 200 kDa antigen expressed on all leucocytes; MEM-31, against the T8 antigen of the cytotoxic/suppressor T-lymphocyte subpopulation; MEM-32, against the T1 antigen of T lymphocytes.
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