Streptomycetes producing daunomycin and related compounds: do we know enough about them after 25 years?
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, historické články, časopisecké články, přehledy
PubMed
2691361
DOI
10.1007/bf02814475
Knihovny.cz E-zdroje
- MeSH
- antibiotika antitumorózní biosyntéza dějiny MeSH
- biotransformace MeSH
- daunomycin biosyntéza dějiny MeSH
- dějiny 20. století MeSH
- mutace MeSH
- Streptomyces genetika metabolismus MeSH
- Check Tag
- dějiny 20. století MeSH
- Publikační typ
- časopisecké články MeSH
- historické články MeSH
- přehledy MeSH
- srovnávací studie MeSH
- Názvy látek
- antibiotika antitumorózní MeSH
- daunomycin MeSH
The growing need of highly potent anticancer agents has stimulated the investigation of streptomycetes producing daunomycin-type anthracyclines. This review compares the features of production strains and their mutants and emphasizes the necessity of application of biochemical and biophysical analytical methods for better understanding these microorganisms and, above all, their further improving and practical usage.
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