The formation of the exoenzymes, neutral and alkaline proteinase as well as alpha-amylase of Bacillus subtilis, is characterized by the same time course. The exoenzyme formation starts in the exponential phase of growth by an excess of C and N sources. We assume that carbon metabolism of pyruvate is responsible for the exoenzyme formation during this growth phase. The proteinase formation at the transient and/or stationary phase of growth is related to amino acid limitation.

Central Institute of Molecular Biology GDR Berlin

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Sporulation and synthesis of extracellular proteinases in Bacillus subtilis are more temperature-sensitive than growth

Cell growth and alpha-amylase production characteristics of Bacillus subtilis