The in vitro cytotoxic effect of bilirubin on human lymphocytes and granulocytes
Language English Country United States Media print
Document type Journal Article
PubMed
4007710
DOI
10.1007/bf02923520
Knihovny.cz E-resources
- MeSH
- Bilirubin pharmacology MeSH
- Adult MeSH
- Fetal Blood cytology MeSH
- Granulocytes drug effects MeSH
- Humans MeSH
- Lymphocytes drug effects MeSH
- Cell Survival drug effects MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Bilirubin MeSH
Using an in vitro cytotoxicity assay (51Cr-release), it was shown that bilirubin exerts a cytotoxic effect on both adult and newborn human lymphocytes after a 1-d incubation of cells with bilirubin. The effect of bilirubin on human granulocytes was less pronounced; the association of the cytotoxic effect with a functional immunological perturbation of these cells is discussed.
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Cesk Pediatr. 1980 Jul;35(7):351-5 PubMed
Sabouraudia. 1979 Jun;17(2):125-9 PubMed
Pediatrics. 1970 Jan;45(1):102-4 PubMed
J Clin Lab Immunol. 1984 Mar;13(3):145-9 PubMed
Gac Med Mex. 1973 Feb;105(2):185-207 PubMed
Folia Microbiol (Praha). 1980;25(6):483-90 PubMed
Folia Microbiol (Praha). 1981;26(5):413-6 PubMed
Transplantation. 1965 May;3:423-31 PubMed
Biol Neonate. 1982;42(3-4):152-8 PubMed
Helv Paediatr Acta. 1977 Jul;32(2):129-33 PubMed
Acta Paediatr Scand. 1977 Nov;66(6):757-9 PubMed
Immunology. 1965 Sep;9(3):287-300 PubMed
Biomed Biochim Acta. 1983;42(5):503-10 PubMed
J Pediatr. 1969 Feb;74(2):240-6 PubMed
Folia Microbiol (Praha). 1979;24(2):143-52 PubMed
J Pediatr. 1975 May;86(5):690-6 PubMed
Klin Padiatr. 1977 Nov;189(6):393-400 PubMed
Biochem Med. 1971 Feb;5(1):1-16 PubMed
Pediatr Clin North Am. 1972 May;19(2):447-501 PubMed
Am J Dis Child. 1968 Mar;115(3):358-61 PubMed
The immunosuppressive effects of bilirubin
