Based on recombinants between the B haplotypes of chickens of inbred lines CB, CC, and CB.I-B7, three new inbred lines homogeneous in transplantation and erythrocyte antigens were established by backcrossing. These newly established recombinant lines, CB.R1, CC.R1, and CC.R2, together with the original inbred lines, which differ at the B complex (MHC) and in the degree of genetically controlled resistance to progressive growth of RSV-induced tumours, represent a model system for study of the structure of the B complex and of the functions of individual B regions in the control of carcinogenesis.

Cytokine response to the RSV antigen delivered by dendritic cell-directed vaccination in congenic chicken lines

Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling

The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells

Molecular genotyping of recombinant congenic lines provides evidence for crossing-over within the B-G region of the major histocompatibility complex of the chicken

Tumor induction by the LTR, v-src, LTR DNA in four B (MHC) congenic lines of chickens