Genetic markers in hypercholesterolemic and normocholesterolemic Czech children
Clinical genetics.
1994 Jul ;
46 (1 Spec No) :
88-91.
Language English Country Denmark Media print
Document type Journal Article
Persistent link
https://www.medvik.cz/link/pmid07988085
- MeSH
- Apolipoproteins B genetics MeSH
- Apolipoproteins E genetics MeSH
- Child MeSH
- Genetic Markers MeSH
- Hyperlipoproteinemia Type II genetics MeSH
- Receptors, LDL genetics MeSH
- Humans MeSH
- Chromosome Mapping MeSH
- Polymorphism, Genetic MeSH
- Reference Values MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czechoslovakia MeSH
- Names of Substances
- Apolipoproteins B MeSH
- Apolipoproteins E MeSH
- Genetic Markers MeSH
- Receptors, LDL MeSH
The genetic background of polygenic hypercholesterolemia was studied in hypercholesterolemic children consuming a diet identical to control individuals with low cholesterol concentrations. Significantly higher frequencies of "disadvantage" alleles, usually combined with a higher LDL cholesterol, were found in hypercholesterolemic individuals when polymorphisms in apolipoprotein E, apolipoprotein B--XbaI and LDL receptor--PvuII were studied.
References provided by Crossref.org
International journal of molecular sciences.
2021 Apr 17 ;
22 (8) :
.
[epub] 20210417
