Fungicide inhibition of aflatoxins, diacetoxyscirpenol and zearalenone production
Language English Country United States Media print
Document type Journal Article
PubMed
8112694
DOI
10.1007/bf02898597
Knihovny.cz E-resources
- MeSH
- Aflatoxins antagonists & inhibitors biosynthesis MeSH
- alpha-Amylases metabolism MeSH
- Aminoimidazole Carboxamide analogs & derivatives pharmacology MeSH
- Aniline Compounds pharmacology MeSH
- Aspergillus flavus drug effects enzymology metabolism MeSH
- Fusarium drug effects enzymology MeSH
- Hydantoins * MeSH
- Mycotoxins antagonists & inhibitors biosynthesis MeSH
- Oxazoles pharmacology MeSH
- Fungicides, Industrial pharmacology MeSH
- Trichothecenes antagonists & inhibitors biosynthesis MeSH
- Zearalenone antagonists & inhibitors biosynthesis MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Aflatoxins MeSH
- alpha-Amylases MeSH
- Aminoimidazole Carboxamide MeSH
- Aniline Compounds MeSH
- diacetoxyscirpenol MeSH Browser
- dicloran MeSH Browser
- Hydantoins * MeSH
- iprodione MeSH Browser
- Mycotoxins MeSH
- Oxazoles MeSH
- Fungicides, Industrial MeSH
- Trichothecenes MeSH
- vinclozolin MeSH Browser
- Zearalenone MeSH
The effect of fungicides on the production of aflatoxin by Aspergillus flavus IMI 89717, diacetoxyscirpenol and zearalenone by Fusarium graminearum was studied. In a yeast extract-sucrose medium, dicloran, iprodione and vinclozolin fungicides significantly inhibited mycelial growth of A. flavus at 250 ppm and significantly decreased aflatoxin production at 100, 250 and 500 ppm, respectively. In potato-dextrose broth, these fungicides diminished the mycelial growth of F. graminearum and production of diacetoxyscirpenol and zearalenone at 100 ppm. Sensitivity of toxigenic mycelia to fungicides increased approximately five-fold in a yeast extract-starch medium with an appreciable reduction in sugar uptake and alpha-amylase activity.
