Involution of the Wolffian duct in the rat
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
8167402
Knihovny.cz E-resources
- MeSH
- Microscopy, Electron MeSH
- Rats MeSH
- Rats, Wistar anatomy & histology MeSH
- Sex Differentiation MeSH
- Wolffian Ducts embryology ultrastructure MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
The involution of Wolffian duct in female rat fetuses from 15 to 21 days of gestation was studied in electron microscope. The female Wolffian duct stopped its differentiation on day 17 and the onset of duct regression was found in 18 days old fetuses. The involution was accompanied by degeneration and disintegration of epithelial cells, removal of basal lamina and elimination of altered cells into periductal mesenchyme. Although the mechanism of programmed cell death contributed to the WD regression the findings of non-altered epithelial cells supported the opinion of possible migration of some WD cells into the mesenchymal cell compartment.
