Hybrid sterility in the mouse

. 1996 Oct ; 12 (10) : 412-7.

Jazyk angličtina Země Anglie, Velká Británie Médium print

Typ dokumentu časopisecké články, práce podpořená grantem, Research Support, U.S. Gov't, P.H.S., přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid08909138

Grantová podpora
IRO1 D28395 01 A1 PHS HHS - United States

Odkazy

PubMed 8909138
DOI 10.1016/0168-9525(96)10040-8
PII: 0168-9525(96)10040-8
Knihovny.cz E-zdroje

The sterility of hybrids between various mouse species follows Haldane's rule by affecting only the males. Hitherto, five hybrid sterility (Hst) loci have been identified in the mouse genome. Haldane's rule holds also for chromosomal sterility in all studied mammalian species, including man. The males heterozygous for various male-sterile chromosomal rearrangements show the same meiotic phenotype: partially asynaptic, rearranged autosomes associate with the X Chromosome. Thus, the X-Chromosome inactivation in the male meiosis might function as a checkpoint leading to the meiotic arrest in sterile hybrids. Chromosomal and gene hybrid sterility might be interrelated because the attributes of chromosomal sterility, such as X-autosome associations, occur also in interspecies hybrids with genic sterility.

Erratum v

Trends Genet 1997 Jan;13(1):42 PubMed

Citace poskytuje Crossref.org

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