Electrophoretic karyotyping of Candida albicans strains isolated from premature infants and hospital personnel in a neonatal intensive care unit
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, časopisecké články
PubMed
11899481
DOI
10.1007/bf02814438
Knihovny.cz E-zdroje
- MeSH
- Candida albicans genetika izolace a purifikace MeSH
- fungemie mikrobiologie MeSH
- infekce spojené se zdravotní péčí mikrobiologie přenos MeSH
- jednotky intenzivní péče o novorozence * MeSH
- kandidóza epidemiologie mikrobiologie přenos MeSH
- karyotypizace MeSH
- lidé MeSH
- novorozenec nedonošený krev MeSH
- novorozenec MeSH
- personál nemocniční * MeSH
- přenos infekce ze zdravotnického pracovníka na pacienta MeSH
- prospektivní studie MeSH
- ruka MeSH
- zdravotní sestry MeSH
- Check Tag
- lidé MeSH
- novorozenec MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Geografické názvy
- Slovenská republika epidemiologie MeSH
Electrophoretic karyotyping was used to compare DNA probes of yeasts isolated from blood of preterm neonates (n = 66) in a neonatal intensive care unit (NICU) and from the hands of healthy hospital personnel (n = 10). The yeasts were identified as Candida albicans using standard laboratory methods. DNA was extracted from yeasts and isolation of identical DNA strains from the pairs nurse-neonate suggested that one nurse transmitted one yeast strain by her hands to three neonates. Four neonates harbored two identical strains originating from two nurses, i.e. each nurse transmitted the same strain to two neonates. In the additional 7 cases transmission of 1 yeast strain by 1 nurse to 1 neonate was observed. Our data suggest that nonperinatal nosocomial transmission of C. albicans occurs in neonates, possibly via cross-contamination being transferred on hands of health care workers. The importance of careful hand washing of staff (health care workers) and other infection-control procedures (to prevent the nosocomial transmission of pathogens in the NICU environment) is emphasized.
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