Plasma ghrelin levels and malnutrition: a comparison of two etiologies

. 2003 Sep ; 8 (3) : 207-11.

Jazyk angličtina Země Německo Médium print

Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid14649784

Ghrelin is a peptide hormone that is involved in regulating growth hormone secretion as well as food intake and energy homeostasis. The aim of this study was to compare changes in plasma ghrelin levels in patients with malnutrition due to anorexia nervosa (AN) or short bowel syndrome (SBS). Blood samples for laboratory analyses were taken from 16 AN patients (plus 13 comparable healthy controls) and 27 SBS patients (plus 13 comparable healthy controls) after an overnight fast. In comparison with their respective control groups, plasma ghrelin levels were increased in the AN patients (p < 0.05) and significantly decreased in the patients with SBS (p < 0.01). These results suggest that quantitative ghrelin secretion in the gut wall is important in determining ghrelin concentrations in the systemic circulation.

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Biochem Biophys Res Commun. 2001 Jan 26;280(3):904-7 PubMed

J Clin Endocrinol Metab. 2000 Oct;85(10):3803-7 PubMed

Nature. 2000 Oct 19;407(6806):908-13 PubMed

J Clin Invest. 1997 Aug 15;100(4):808-13 PubMed

Nature. 1999 Dec 9;402(6762):656-60 PubMed

Endocrinology. 2000 Nov;141(11):4255-61 PubMed

J Clin Endocrinol Metab. 2001 Oct;86(10):4753-8 PubMed

J Clin Endocrinol Metab. 1997 Aug;82(8):2510-3 PubMed

Diabetes. 2001 Apr;50(4):707-9 PubMed

Endocrinology. 2000 Nov;141(11):4325-8 PubMed

Eat Weight Disord. 1998 Jun;3(2):64-70 PubMed

Gastroenterologist. 1996 Jun;4(2):118-28 PubMed

Growth Horm IGF Res. 2001 Apr;11(2):117-27 PubMed

Eur J Endocrinol. 2001 Nov;145(5):669-73 PubMed

Biochem Biophys Res Commun. 2000 Oct 5;276(3):905-8 PubMed

Endocr Res. 2002 Feb-May;28(1-2):27-33 PubMed

Physiol Res. 1999;48(3):197-202 PubMed

Endocrinology. 1984 May;114(5):1537-45 PubMed

Gastroenterology. 2001 Feb;120(2):337-45 PubMed

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