Angiogenesis and organ transplantation
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
15702536
DOI
10.1007/bf02931524
Knihovny.cz E-resources
- MeSH
- Angiopoietins physiology MeSH
- Models, Biological MeSH
- Fibroblast Growth Factor 2 physiology MeSH
- Neovascularization, Physiologic * MeSH
- Hepatocyte Growth Factor physiology MeSH
- Kidney blood supply injuries MeSH
- Humans MeSH
- Ribonuclease, Pancreatic physiology MeSH
- Neovascularization, Pathologic * MeSH
- Graft Rejection MeSH
- Transforming Growth Factor beta physiology MeSH
- Transforming Growth Factor beta1 MeSH
- Organ Transplantation * MeSH
- Vascular Endothelial Growth Factor A physiology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- angiogenin MeSH Browser
- Angiopoietins MeSH
- Fibroblast Growth Factor 2 MeSH
- Hepatocyte Growth Factor MeSH
- Ribonuclease, Pancreatic MeSH
- TGFB1 protein, human MeSH Browser
- Transforming Growth Factor beta MeSH
- Transforming Growth Factor beta1 MeSH
- Vascular Endothelial Growth Factor A MeSH
Angiogenesis is a vessel development process that maintains the vascular supply for organ function. Regulation of angiogenesis is provided by positive factors, such as vascular endothelial or basic fibroblast growth factors, and negative factors, such as thrombospondin and macrophage-derived inflammatory cytokines. While the role of angiogenesis in the wound healing, embryogenesis, tumor growth and proliferative diseases is clear, in organ transplantation it is not yet well established. Herein we discuss the potential role of angiogenesis in chronic renal disease and in transplant settings.
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