Learning in the Place navigation task, not the New-learning task, is altered by prenatal methamphetamine exposure
Language English Country Netherlands Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
15936828
DOI
10.1016/j.devbrainres.2005.04.005
PII: S0165-3806(05)00129-X
Knihovny.cz E-resources
- MeSH
- Maze Learning drug effects physiology MeSH
- Rats MeSH
- Methamphetamine adverse effects MeSH
- Disease Models, Animal MeSH
- Brain drug effects growth & development physiopathology MeSH
- Orientation drug effects physiology MeSH
- Memory drug effects physiology MeSH
- Sex Characteristics MeSH
- Memory Disorders chemically induced physiopathology MeSH
- Amphetamine-Related Disorders physiopathology MeSH
- Learning Disabilities chemically induced physiopathology MeSH
- Rats, Wistar MeSH
- Sex Factors MeSH
- Central Nervous System Stimulants adverse effects MeSH
- Pregnancy MeSH
- Prenatal Exposure Delayed Effects * MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Pregnancy MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Methamphetamine MeSH
- Central Nervous System Stimulants MeSH
Adult rats (prenatally methamphetamine-exposed, saline-exposed and controls) were tested for learning in the Morris water maze. Rats were tested in 4 consecutive days using two different types of learning tests: "Place navigation test" (stable platform position) and "New-learning test" (platform position changed daily). Males exposed prenatally to methamphetamine were slower in the Place navigation learning test than were both the control and saline-exposed males. There were no differences in the New-learning test between groups.
References provided by Crossref.org
Prenatal Exposure to Methamphetamine: Up-Regulation of Brain Receptor Genes
Age-related differences in NMDA receptor subunits of prenatally methamphetamine-exposed male rats
