Macroporous hydrogels based on 2-hydroxyethyl methacrylate. Part II. Copolymers with positive and negative charges, polyelectrolyte complexes
Language English Country United States Media print
Document type Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Biocompatible Materials analysis chemistry pharmacology MeSH
- Electrolytes analysis chemistry MeSH
- Hydrogels analysis chemistry pharmacology MeSH
- Rats MeSH
- Macromolecular Substances analysis chemistry MeSH
- Methacrylates analysis chemistry pharmacology MeSH
- Connective Tissue drug effects ultrastructure MeSH
- Polymers analysis chemistry MeSH
- Porosity MeSH
- Surface Properties MeSH
- Static Electricity MeSH
- Materials Testing MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Evaluation Study MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Names of Substances
- Biocompatible Materials MeSH
- Electrolytes MeSH
- Hydrogels MeSH
- hydroxyethyl methacrylate MeSH Browser
- Macromolecular Substances MeSH
- Methacrylates MeSH
- Polymers MeSH
Crosslinked macroporous hydrogels based on 2-hydroxyethyl methacrylate (HEMA)-[2-(methacryloyloxy)ethyl]trimethylammonium chloride (MOETACl) copolymer, HEMA-MOETACl-methacrylic acid (MA) terpolymer, and on a polyelectrolyte complex of HEMA-MA copolymer with poly(MOETACl) were prepared. All the hydrogels were prepared in the presence of fractionated sodium chloride particles. The hydrogels were characterized by the number of pores and the total volume of all pores in unit volume, the average volume and the average diameter of single pore. Morphology of the hydrogels was investigated by confocal and scanning electron microscopy. The hydrogels based on polyelectrolyte complexes were also characterized by chemical composition. Homogeneous (non-porous) hydrogels with the same composition as macroporous hydrogels were prepared and characterized by their biocompatibility.
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