Early diastolic mitral annular velocity and color M-mode flow propagation velocity in the evaluation of left ventricular diastolic function in patients with Fabry disease
Jazyk angličtina Země Japonsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- barevná dopplerovská echokardiografie * MeSH
- dospělí MeSH
- dysfunkce levé srdeční komory diagnostické zobrazování patofyziologie MeSH
- Fabryho nemoc diagnostické zobrazování patofyziologie MeSH
- falešně negativní reakce MeSH
- funkce levé komory srdeční * MeSH
- hypertrofie levé komory srdeční diagnostické zobrazování patofyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mitrální chlopeň diagnostické zobrazování patofyziologie MeSH
- plocha pod křivkou MeSH
- počítačové zpracování obrazu MeSH
- pulzní dopplerovská echokardiografie MeSH
- remodelace komor MeSH
- retrospektivní studie MeSH
- rychlost toku krve MeSH
- senzitivita a specificita MeSH
- srdeční síně diagnostické zobrazování patofyziologie MeSH
- tepový objem * MeSH
- výzkumný projekt MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Fabry disease is an X-linked genetic disorder characterized by progressive intracellular accumulation of neutral glycosphingolipids. Cardiac involvement is frequent and left ventricular (LV) diastolic dysfunction is present in most of the affected subjects. Pulsed-wave tissue Doppler echocardiography (PW-TDE) and color M-mode are new Doppler methods for LV diastolic function evaluation. Their role in the assessment of Fabry disease-related cardiomyopathy remains to be established. In this study we aimed to determine the utility of PW-TDE and color M-mode-derived parameters in the assessment of LV diastolic function in patients with Fabry disease. Eighty-one echocardiographic examinations performed in 35 patients affected by Fabry disease were retrospectively analyzed. Early diastolic lateral mitral annular velocity (E(m)) determined by PW-TDE and color M-mode flow propagation velocity (V(p)) were measured and compared to LV filling patterns obtained using standard Doppler indexes. The receiver operating characteristics (ROC) curves method was used to determine the summary measure of relative accuracy for E(m) and V(p). A comparison of ROC curves showed a significant difference for areas under the curve in favor of E(m) (P < 0.001). Pseudonormal filling pattern, higher LV mass index, higher relative wall thickness, larger left atrial diameter, and older age were more frequent (all P < 0.001) in patients with incorrect diagnosis of normal LV diastolic function based on the measurement of V(p). E(m) appears to be superior to V(p) in the assessment of LV diastolic function in patients with Fabry disease. V(p) fails to detect abnormal LV diastolic function in subjects with pronounced concentric LV remodeling and pseudonormal filling pattern.
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Am J Cardiol. 2002 Sep 15;90(6):613-9 PubMed
J Am Soc Echocardiogr. 1999 Aug;12 (8):618-28 PubMed
J Am Coll Cardiol. 1996 Jan;27(1):108-14 PubMed
Eur J Echocardiogr. 2004 Jun;5(3):196-204 PubMed
Cardiol Clin. 2000 Aug;18(3):513-46, ix PubMed
J Am Coll Cardiol. 1989 Apr;13(5):1017-26 PubMed
J Am Coll Cardiol. 1988 Aug;12(2):426-40 PubMed
Circulation. 2003 Apr 22;107(15):1978-84 PubMed
Circulation. 2000 Oct 10;102(15):1788-94 PubMed
Am J Cardiol. 1987 Apr 15;59(9):956-60 PubMed
J Am Coll Cardiol. 1992 Aug;20(2):420-32 PubMed
Biochim Biophys Acta. 1997 Apr 1;1345(2):180-7 PubMed
Circulation. 1986 Jul;74(1):187-96 PubMed
J Am Coll Cardiol. 1997 Aug;30(2):474-80 PubMed
Am J Cardiol. 1986 Feb 15;57(6):450-8 PubMed
J Am Soc Echocardiogr. 1997 Apr;10 (3):271-92 PubMed
J Am Soc Echocardiogr. 1999 Feb;12(2):129-37 PubMed
Circulation. 1978 Dec;58(6):1072-83 PubMed
J Am Coll Cardiol. 1997 Jul;30(1):8-18 PubMed
Ann Intern Med. 1991 Mar 1;114(5):345-52 PubMed
Am Heart J. 1996 May;131(5):982-7 PubMed
Am J Cardiol. 1997 Apr 1;79(7):921-8 PubMed
Am J Cardiol. 2003 Mar 15;91(6):780-4 PubMed
Heart Vessels. 2003 Mar;18(1):1-6 PubMed
J Am Soc Echocardiogr. 2000 Nov;13(11):980-5 PubMed
Am Heart J. 1980 Dec;100(6 Pt 1):807-12 PubMed
J Am Soc Echocardiogr. 1996 Sep-Oct;9(5):736-60 PubMed
Am Heart J. 2000 Jun;139(6):1101-8 PubMed
J Am Soc Echocardiogr. 2001 Nov;14 (11):1070-4 PubMed
J Am Coll Cardiol. 2000 Jan;35(1):201-8 PubMed
J Inherit Metab Dis. 2001;24 Suppl 2:75-83; discussion 65 PubMed