Plants are exposed to a temporally and spatially heterogeneous environment, and photosynthesis is well adapted to these fluctuations. Understanding of the complex, non-linear dynamics of photosynthesis in fluctuating light requires novel-modeling approaches that involve not only the primary light and dark biochemical reactions, but also networks of regulatory interactions. This requirement exceeds the capacity of the existing molecular models that are typically reduced to describe a partial process, dynamics of a specific complex or its particular dynamic feature. We propose a concept of comprehensive model that would represent an internally consistent, integral framework combining information on the reduced models that led to its construction. This review explores approaches and tools that exist in engineering, mathematics, and in other domains of biology that can be used to develop a comprehensive model of photosynthesis. Equally important, we investigated techniques by which one can rigorously reduce such a comprehensive model to models of low dimensionality, which preserve dynamic features of interest and, thus, contribute to a better understanding of photosynthesis under natural and thus fluctuating conditions. The web-based platform www.e-photosynthesis.org is introduced as an arena where these concepts and tools are being introduced and tested.

Institute of Systems Biology and Ecology ASCR Zámek 136 37333 Nove Hrady Czech Republic

Zobrazit více v PubMed

Chem Rev. 1998 Apr 2;98(2):391-408 PubMed

Funct Plant Biol. 2006 Feb;33(1):9-30 PubMed

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11801-5 PubMed

Biophys J. 2006 Jan 15;90(2):552-65 PubMed

Science. 2002 Mar 1;295(5560):1664-9 PubMed

Planta. 1992 Aug;188(1):28-38 PubMed

Plant Methods. 2006 Jan 09;2:1 PubMed

Biochim Biophys Acta. 1999 May 26;1412(1):1-28 PubMed

Syst Biol (Stevenage). 2004 Jun;1(1):149-58 PubMed

Photosynth Res. 1990 Sep;25(3):151-60 PubMed

Curr Opin Plant Biol. 2006 Dec;9(6):671-8 PubMed

Biochim Biophys Acta. 2003 Oct 17;1607(1):5-17 PubMed

Science. 2002 Mar 1;295(5560):1662-4 PubMed

Science. 2002 Jul 5;297(5578):91-3 PubMed

Biophys J. 2005 Sep;89(3):1464-81 PubMed

Plant Physiol. 2001 Jan;125(1):42-5 PubMed

Plant Physiol. 1997 Apr;113(4):1309-1317 PubMed

Photosynth Res. 2003;76(1-3):329-41 PubMed

Biophys J. 1995 Jun;68(6):2474-92 PubMed

FEBS J. 2006 Nov;273(21):4862-77 PubMed

Plant Physiol. 2003 Jun;132(2):404-9 PubMed

Mol Syst Biol. 2006;2:2006.0010 PubMed

Photosynth Res. 2005 Jun;84(1-3):99-106 PubMed

Phys Chem Chem Phys. 2006 Feb 21;8(7):793-807 PubMed

Photosynth Res. 2002 Apr;72(1):95-106 PubMed

Biophys J. 2003 Dec;85(6):3899-922 PubMed

Photosynth Res. 1986 Jan;10(1-2):51-62 PubMed

Biochim Biophys Acta. 1999 Jan 5;1409(3):125-42 PubMed

Appl Opt. 2006 Jul 1;45(19):4726-39 PubMed

J Exp Bot. 2004 May;55(400):1177-86 PubMed

J Exp Bot. 2000 Feb;51 Spec No:319-28 PubMed

Proc Natl Acad Sci U S A. 2006 May 2;103(18):6895-900 PubMed

Proc Biol Sci. 2001 Jun 22;268(1473):1307-13 PubMed

FEBS J. 2005 Aug;272(16):4034-43 PubMed

Bioinformatics. 2003 Mar 1;19(4):524-31 PubMed